ASMER1

Summary

ASMER1 (adipocyte associated metabolic related lncRNA 1, HGNC:53135) is a long non-coding RNA gene on chromosome 21q11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53135
Approved symbol	ASMER1
Name	adipocyte associated metabolic related lncRNA 1
Location	21q11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000418954, ASMER-1
Ensembl gene	ENSG00000281903
Ensembl biotype	lncRNA
Entrez	107987295
RNAcentral	URS0000BC4618 — lncRNA, 8345 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 30 — 30 lncRNA

ENST00000412426, ENST00000418954, ENST00000432230, ENST00000625278, ENST00000627623, ENST00000630211, ENST00000630354, ENST00000715450, ENST00000715451, ENST00000715452, ENST00000715453, ENST00000715454, ENST00000715455, ENST00000715456, ENST00000715457, ENST00000715458, ENST00000715910, ENST00000794242, ENST00000794243, ENST00000794244, ENST00000794245, ENST00000794246, ENST00000794247, ENST00000794248, ENST00000794249, ENST00000794250, ENST00000794251, ENST00000794252, ENST00000794253, ENST00000850670

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412426 — 4 exons

Exon	Start	End
ENSE00003766821	14857542	14857708
ENSE00004026817	14853274	14853431
ENSE00004177906	14881887	14882014
ENSE00004177921	14835529	14837823

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 96.01.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.7209 / max 618.1698, expressed in 64 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
189803	0.6660	49
189805	0.0550	19

Top tissues by expression

136 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	96.01	gold quality
cerebellar vermis	UBERON:0004720	94.18	gold quality
placenta	UBERON:0001987	91.01	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.62	gold quality
thymus	UBERON:0002370	81.19	silver quality
adrenal tissue	UBERON:0018303	75.61	gold quality
stromal cell of endometrium	CL:0002255	70.79	gold quality
colonic epithelium	UBERON:0000397	70.47	silver quality
ventricular zone	UBERON:0003053	70.35	gold quality
bone marrow cell	CL:0002092	69.30	silver quality
cortical plate	UBERON:0005343	67.88	gold quality
skeletal muscle tissue	UBERON:0001134	67.07	gold quality
liver	UBERON:0002107	66.58	gold quality
monocyte	CL:0000576	65.87	gold quality
ganglionic eminence	UBERON:0004023	65.28	gold quality
leukocyte	CL:0000738	65.20	gold quality
islet of Langerhans	UBERON:0000006	65.19	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.90	gold quality
sural nerve	UBERON:0015488	63.54	silver quality
tonsil	UBERON:0002372	60.85	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.80	gold quality
rectum	UBERON:0001052	60.73	gold quality
prefrontal cortex	UBERON:0000451	60.70	gold quality
bone marrow	UBERON:0002371	60.39	gold quality
pancreas	UBERON:0001264	60.31	gold quality
urinary bladder	UBERON:0001255	59.84	gold quality
smooth muscle tissue	UBERON:0001135	59.64	gold quality
right lobe of liver	UBERON:0001114	59.23	gold quality
subcutaneous adipose tissue	UBERON:0002190	59.07	gold quality
adrenal gland	UBERON:0002369	58.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.52

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.