ATXN1-AS1

Summary

ATXN1-AS1 (ATXN1 antisense RNA 1, HGNC:40515) is a long non-coding RNA gene on chromosome 6p22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40515
Approved symbol	ATXN1-AS1
Name	ATXN1 antisense RNA 1
Location	6p22.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AL137003.1
Ensembl gene	ENSG00000229931
Ensembl biotype	lncRNA
Entrez	101928433
RNAcentral	URS0000A76F77 — lncRNA, 4736 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000423260, ENST00000450930, ENST00000606924, ENST00000685689, ENST00000689080, ENST00000692306, ENST00000693115, ENST00000701248, ENST00000840856, ENST00000840857, ENST00000840858, ENST00000840859, ENST00000840860, ENST00000840861, ENST00000840862, ENST00000840863, ENST00000840864, ENST00000840865, ENST00000840866, ENST00000840867, ENST00000840868, ENST00000840869, ENST00000840870, ENST00000840871, ENST00000840872, ENST00000840873, ENST00000840874, ENST00000840875, ENST00000840876

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000423260 — 3 exons

Exon	Start	End
ENSE00001681473	16762119	16762279
ENSE00004264638	16762352	16763947
ENSE00004264650	16761064	16761166

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 91.13.

FANTOM5 (CAGE): breadth broad, TPM avg 1.6314 / max 28.7072, expressed in 781 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
66112	1.1691	630
66111	0.3054	143
66113	0.1569	44

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	91.13	gold quality
gall bladder	UBERON:0002110	77.88	gold quality
popliteal artery	UBERON:0002250	77.48	gold quality
body of uterus	UBERON:0009853	77.46	gold quality
tibial artery	UBERON:0007610	77.44	gold quality
cortical plate	UBERON:0005343	77.34	gold quality
adenohypophysis	UBERON:0002196	76.40	gold quality
bone marrow cell	CL:0002092	76.20	gold quality
pituitary gland	UBERON:0000007	75.82	gold quality
right lobe of liver	UBERON:0001114	75.62	gold quality
smooth muscle tissue	UBERON:0001135	75.59	gold quality
aorta	UBERON:0000947	75.52	gold quality
left lobe of thyroid gland	UBERON:0001120	74.34	gold quality
stromal cell of endometrium	CL:0002255	73.84	gold quality
right coronary artery	UBERON:0001625	73.82	gold quality
ascending aorta	UBERON:0001496	73.52	gold quality
right atrium auricular region	UBERON:0006631	73.51	gold quality
thoracic aorta	UBERON:0001515	73.39	gold quality
right lung	UBERON:0002167	73.37	gold quality
muscle layer of sigmoid colon	UBERON:0035805	73.37	gold quality
thyroid gland	UBERON:0002046	73.06	gold quality
left coronary artery	UBERON:0001626	72.73	gold quality
right uterine tube	UBERON:0001302	72.67	gold quality
cardiac atrium	UBERON:0002081	72.67	gold quality
prefrontal cortex	UBERON:0000451	72.54	gold quality
right frontal lobe	UBERON:0002810	72.47	gold quality
ectocervix	UBERON:0012249	72.32	gold quality
buccal mucosa cell	CL:0002336	72.31	silver quality
left uterine tube	UBERON:0001303	72.15	gold quality
descending thoracic aorta	UBERON:0002345	71.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.19

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.