ATXN7L3-AS1

Summary

ATXN7L3-AS1 (ATXN7L3 antisense RNA 1, HGNC:55298) is a long non-coding RNA gene on chromosome 17q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55298
Approved symbol	ATXN7L3-AS1
Name	ATXN7L3 antisense RNA 1
Location	17q21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267394
Ensembl biotype	lncRNA
Entrez	101926967
RNAcentral	URS00026A1A68 — lncRNA, 1337 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000563394, ENST00000586560, ENST00000588279, ENST00000689614, ENST00000717216, ENST00000848873, ENST00000848874, ENST00000848875, ENST00000848876, ENST00000848877, ENST00000848878

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000563394 — 1 exons

Exon	Start	End
ENSE00002630329	44221915	44223710

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 72.34.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1389 / max 21.6798, expressed in 37 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
161125	0.1389	37

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	72.34	gold quality
monocyte	CL:0000576	70.58	gold quality
leukocyte	CL:0000738	69.96	gold quality
blood	UBERON:0000178	69.87	gold quality
lower esophagus mucosa	UBERON:0035834	69.80	gold quality
mucosa of transverse colon	UBERON:0004991	66.08	gold quality
ganglionic eminence	UBERON:0004023	65.71	gold quality
bone marrow	UBERON:0002371	65.64	gold quality
vermiform appendix	UBERON:0001154	63.75	gold quality
bone marrow cell	CL:0002092	63.45	silver quality
colonic epithelium	UBERON:0000397	61.92	silver quality
lymph node	UBERON:0000029	61.79	gold quality
cortical plate	UBERON:0005343	61.65	gold quality
duodenum	UBERON:0002114	61.29	gold quality
esophagus mucosa	UBERON:0002469	61.17	gold quality
endometrium	UBERON:0001295	61.05	gold quality
placenta	UBERON:0001987	61.04	gold quality
stromal cell of endometrium	CL:0002255	60.97	gold quality
tonsil	UBERON:0002372	60.77	gold quality
skeletal muscle tissue	UBERON:0001134	59.71	gold quality
saliva-secreting gland	UBERON:0001044	59.48	gold quality
islet of Langerhans	UBERON:0000006	58.99	gold quality
minor salivary gland	UBERON:0001830	58.89	gold quality
gall bladder	UBERON:0002110	58.88	gold quality
transverse colon	UBERON:0001157	58.61	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.24	gold quality
mucosa of stomach	UBERON:0001199	57.97	gold quality
body of stomach	UBERON:0001161	57.48	gold quality
esophagus	UBERON:0001043	57.46	gold quality
spleen	UBERON:0002106	57.01	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.