BACH1-AS1

Summary

BACH1-AS1 (BACH1 antisense RNA 1, HGNC:40008) is a long non-coding RNA gene on chromosome 21q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40008
Approved symbol	BACH1-AS1
Name	BACH1 antisense RNA 1
Location	21q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232118
Ensembl biotype	lncRNA
Entrez	106478962
RNAcentral	URS0000776B75 — lncRNA, 700 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000449923, ENST00000615718

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449923 — 2 exons

Exon	Start	End
ENSE00001657359	29370019	29370120
ENSE00001743205	29371088	29371226

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 87.99.

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.99	gold quality
colonic epithelium	UBERON:0000397	86.91	gold quality
bone marrow cell	CL:0002092	79.76	gold quality
cortical plate	UBERON:0005343	78.94	gold quality
corpus callosum	UBERON:0002336	76.22	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.81	silver quality
skeletal muscle tissue	UBERON:0001134	70.88	gold quality
bone marrow	UBERON:0002371	69.70	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.79	gold quality
blood	UBERON:0000178	68.34	gold quality
gastrocnemius	UBERON:0001388	67.61	gold quality
muscle of leg	UBERON:0001383	67.30	gold quality
monocyte	CL:0000576	67.05	gold quality
sural nerve	UBERON:0015488	64.93	silver quality
ventricular zone	UBERON:0003053	64.63	gold quality
tonsil	UBERON:0002372	62.89	gold quality
liver	UBERON:0002107	60.95	gold quality
adrenal tissue	UBERON:0018303	59.28	gold quality
right coronary artery	UBERON:0001625	58.48	gold quality
ectocervix	UBERON:0012249	58.20	gold quality
islet of Langerhans	UBERON:0000006	58.11	gold quality
right lobe of liver	UBERON:0001114	58.09	gold quality
upper lobe of left lung	UBERON:0008952	58.08	gold quality
stromal cell of endometrium	CL:0002255	58.05	gold quality
lung	UBERON:0002048	57.95	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.59	gold quality
duodenum	UBERON:0002114	57.51	gold quality
placenta	UBERON:0001987	57.24	gold quality
right lung	UBERON:0002167	56.97	gold quality
skin of leg	UBERON:0001511	56.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.73

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Circ_0081001 down-regulates miR-494-3p to enhance BACH1 expression and promotes osteosarcoma progression. (PMID:34191748)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.