BACH1-IT2

Summary

BACH1-IT2 (BACH1 intronic transcript 2, HGNC:40007) is a long non-coding RNA gene on chromosome 21q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40007
Approved symbol	BACH1-IT2
Name	BACH1 intronic transcript 2
Location	21q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228817
Ensembl biotype	lncRNA
Entrez	100874322
RNAcentral	URS000075B326 — lncRNA, 802 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000436529, ENST00000608072, ENST00000626681

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000436529 — 3 exons

Exon	Start	End
ENSE00001634016	29372435	29372563
ENSE00001673483	29373242	29373709
ENSE00003142988	29370947	29371155

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 81.59.

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.59	gold quality
bone marrow cell	CL:0002092	79.96	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.38	gold quality
cortical plate	UBERON:0005343	75.27	gold quality
colonic epithelium	UBERON:0000397	74.33	gold quality
skeletal muscle tissue	UBERON:0001134	74.14	gold quality
monocyte	CL:0000576	73.01	gold quality
blood	UBERON:0000178	72.90	gold quality
leukocyte	CL:0000738	72.82	gold quality
gastrocnemius	UBERON:0001388	72.59	gold quality
muscle of leg	UBERON:0001383	71.39	gold quality
stromal cell of endometrium	CL:0002255	70.20	gold quality
bone marrow	UBERON:0002371	70.08	gold quality
granulocyte	CL:0000094	69.35	gold quality
ganglionic eminence	UBERON:0004023	68.83	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.67	gold quality
ventricular zone	UBERON:0003053	66.37	gold quality
lower esophagus mucosa	UBERON:0035834	65.62	gold quality
liver	UBERON:0002107	64.56	gold quality
tonsil	UBERON:0002372	64.37	gold quality
spleen	UBERON:0002106	63.22	gold quality
skin of abdomen	UBERON:0001416	63.15	gold quality
zone of skin	UBERON:0000014	62.93	gold quality
upper lobe of left lung	UBERON:0008952	62.92	gold quality
metanephros cortex	UBERON:0010533	62.87	gold quality
adrenal tissue	UBERON:0018303	62.77	gold quality
skin of leg	UBERON:0001511	62.55	gold quality
right lung	UBERON:0002167	62.18	gold quality
lung	UBERON:0002048	62.10	gold quality
esophagus mucosa	UBERON:0002469	61.45	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.19

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.