BAHD1

Summary

BAHD1 (bromo adjacent homology domain containing 1, HGNC:29153) is a protein-coding gene on chromosome 15q15.1, encoding Bromo adjacent homology domain-containing 1 protein (Q8TBE0). Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains.

Enables chromatin binding activity. Involved in heterochromatin formation and negative regulation of DNA-templated transcription. Located in nucleoplasm. Part of chromatin silencing complex.

Source: NCBI Gene 22893 — RefSeq curated summary.

At a glance

• GWAS associations: 6
• Clinical variants (ClinVar): 135 total
• MANE Select transcript: NM_014952

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:29153
Approved symbol	BAHD1
Name	bromo adjacent homology domain containing 1
Location	15q15.1
Locus type	gene with protein product
Status	Approved
Aliases	KIAA0945
Ensembl gene	ENSG00000140320
Ensembl biotype	protein_coding
OMIM	613880
Entrez	22893

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 21 protein_coding, 1 retained_intron

ENST00000416165, ENST00000560846, ENST00000561234, ENST00000561464, ENST00000852443, ENST00000852444, ENST00000852445, ENST00000852446, ENST00000852447, ENST00000918911, ENST00000918912, ENST00000918913, ENST00000918914, ENST00000918915, ENST00000918916, ENST00000918917, ENST00000959369, ENST00000959370, ENST00000959371, ENST00000959372, ENST00000959373, ENST00000959374

RefSeq mRNA: 3 — MANE Select: NM_014952 NM_001301132, NM_001411044, NM_014952

CCDS: CCDS10058, CCDS73705, CCDS91980

Canonical transcript exons

ENST00000416165 — 7 exons

Exon	Start	End
ENSE00000942425	40461912	40462294
ENSE00000942426	40463861	40464020
ENSE00000942427	40464471	40464547
ENSE00000942428	40465335	40465435
ENSE00001377571	40458451	40459896
ENSE00001492966	40440953	40441268
ENSE00001629823	40465941	40468236

Expression profiles

Bgee: expression breadth ubiquitous, 274 present calls, max score 91.57.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 10.7170 / max 109.8383, expressed in 1782 samples.

FANTOM5 promoters (7 alternative TSS)

Promoter ID	TPM avg	Samples expressed
146114	6.7873	1744
146116	2.2375	1204
146117	0.6444	381
146115	0.6311	380
146113	0.2017	101
146111	0.1607	63
146112	0.0543	31

Top tissues by expression

290 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
olfactory bulb	UBERON:0002264	91.57	silver quality
granulocyte	CL:0000094	88.93	gold quality
left adrenal gland cortex	UBERON:0035825	88.15	gold quality
right adrenal gland	UBERON:0001233	88.11	gold quality
left adrenal gland	UBERON:0001234	88.03	gold quality
type B pancreatic cell	CL:0000169	88.01	gold quality
upper arm skin	UBERON:0004263	87.79	gold quality
right lobe of thyroid gland	UBERON:0001119	87.75	gold quality
right ovary	UBERON:0002118	87.69	gold quality
adrenal cortex	UBERON:0001235	87.65	gold quality
vena cava	UBERON:0004087	87.48	gold quality
left ovary	UBERON:0002119	87.41	gold quality
adrenal gland	UBERON:0002369	87.23	gold quality
left lobe of thyroid gland	UBERON:0001120	87.21	gold quality
mucosa of transverse colon	UBERON:0004991	87.17	gold quality
right adrenal gland cortex	UBERON:0035827	87.12	gold quality
apex of heart	UBERON:0002098	86.73	gold quality
thyroid gland	UBERON:0002046	86.54	gold quality
cardia of stomach	UBERON:0001162	86.08	gold quality
ovary	UBERON:0000992	85.59	gold quality
right testis	UBERON:0004534	85.40	gold quality
left uterine tube	UBERON:0001303	85.08	gold quality
lower esophagus mucosa	UBERON:0035834	84.92	gold quality
nipple	UBERON:0002030	84.90	gold quality
body of stomach	UBERON:0001161	84.69	gold quality
body of pancreas	UBERON:0001150	84.67	gold quality
left testis	UBERON:0004533	84.60	gold quality
adenohypophysis	UBERON:0002196	84.54	gold quality
thymus	UBERON:0002370	84.51	gold quality
adrenal tissue	UBERON:0018303	84.48	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.95
E-MTAB-6058	no	39.61

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

137 targeting BAHD1, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-30A-5P	100.00	76.31	3233
HSA-MIR-30B-5P	100.00	76.29	3248
HSA-MIR-30C-5P	100.00	76.29	3248
HSA-MIR-30D-5P	100.00	76.32	3233
HSA-MIR-30E-5P	100.00	76.32	3242
HSA-MIR-8485	100.00	77.57	4731
HSA-MIR-9-5P	100.00	72.28	2361
HSA-MIR-6748-5P	100.00	65.81	1057
HSA-MIR-4455	100.00	65.48	1587
HSA-MIR-1277-5P	100.00	73.95	5056
HSA-MIR-6740-5P	100.00	65.64	932
HSA-MIR-3667-3P	99.99	67.17	1636
HSA-MIR-3692-3P	99.98	70.27	2139
HSA-MIR-3065-5P	99.97	71.56	3281
HSA-MIR-551B-5P	99.96	71.28	3493
HSA-MIR-4666A-3P	99.96	71.71	3434
HSA-MIR-302E	99.96	70.74	2669
HSA-MIR-128-3P	99.95	71.17	2484
HSA-MIR-216A-3P	99.95	71.19	2505
HSA-MIR-141-3P	99.94	72.79	2421
HSA-MIR-200A-3P	99.94	72.68	2420
HSA-MIR-454-3P	99.91	74.01	1925
HSA-MIR-106A-5P	99.90	73.94	2683
HSA-MIR-130A-3P	99.90	73.31	1861
HSA-MIR-130B-3P	99.90	73.27	1850
HSA-MIR-301A-3P	99.90	73.15	1839
HSA-MIR-301B-3P	99.90	73.19	1836
HSA-MIR-3666	99.90	73.24	1833
HSA-MIR-4295	99.90	73.11	1838
HSA-MIR-17-5P	99.89	73.83	2665

Literature-anchored findings (GeneRIF, showing 11)

• BAHD1 acts as a silencer by recruiting at specific promoters a set of proteins that coordinate heterochromatin assembly (PMID:19666599)
• findings show a Listeria virulence factor, lmo0438/lntA, could target the chromatin repressor BAHD1 in host cell nucleus to activate interferon-stimulated genes; LntA-BAHD1 interplay may modulate IFN-lambda-mediated immune response to control host colonization (PMID:21252314)
• Authors identified a dilysine motif (K180/K181) in the elbow region of Listeria monocytogenes LntA and a central proline-rich region in human BAHD1 as crucial for the direct LntA-BAHD1 interaction. (PMID:24449750)
• computational approaches leveraging public gene expression data can be used to infer potential genes or proteins for diseases, and BAHD1 might act as an indispensable factor in regulating the cellular inflammatory response in UC. (PMID:26183847)
• The BAH domain of BAHD1 is a histone H3K27me3 reader. (PMID:26850261)
• Biochemical analysis of the BAHD1-associated multiprotein complex identifies MIER proteins as novel partners of BAHD1 and suggests that BAHD1-MIER interaction forms a hub for histone deacetylases and methyltransferases (PMID:26938916)
• EFNA5, BAHD1 and PPP2R5E were particularly good candidates for novel disease loci (PMID:30352868)
• The effect of partial BAHD1 deficiency on behavior was then evaluated on Bahd1 heterozygous male mice, which have no lethal or metabolic phenotypes. Bahd1+/- mice showed anxiety-like behavior and reduced prepulse inhibition (PPI) of the startle response. (PMID:32407325)
• FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis. (PMID:33156908)
• A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing. (PMID:33823544)
• BAHD1 serves as a critical regulator of breast cancer cell proliferation and invasion. (PMID:35048286)

Cross-species orthologs

5 orthologs

Organism	Symbol	Gene ID
danio_rerio	bahd1	ENSDARG00000086789
danio_rerio		ENSDARG00000102965
mus_musculus	Bahd1	ENSMUSG00000040007
rattus_norvegicus	Bahd1	ENSRNOG00000010428
drosophila_melanogaster	wge	FBGN0051151

Paralogs (2): TNRC18 (ENSG00000182095), BAHCC1 (ENSG00000266074)

Protein

Protein identifiers

Bromo adjacent homology domain-containing 1 protein — Q8TBE0 (reviewed: Q8TBE0)

All UniProt accessions (1): Q8TBE0

UniProt curated annotations — full annotation on UniProt →

Function. Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. May act by recruiting heterochromatin proteins such as CBX5 (HP1 alpha), HDAC5 and MBD1. Represses IGF2 expression by binding to its CpG-rich P3 promoter and recruiting heterochromatin proteins. At specific stages of Listeria infection, in complex with TRIM28, corepresses interferon-stimulated genes, including IFNL1, IFNL2 and IFNL3.

Subunit / interactions. Interacts with CBX5 (HP1 alpha), HDAC5, MBD1 and SP1. Forms a transcription silencing complex with at least CBX3 (HP1 gamma), HDAC1, HDAC2 and TRIM28. Interacts with L.monocytogenes LntA; this interaction, occurring at a late Listeria infection stage, relieves transcription repression, mostly that of interferon-stimulated genes. Interacts with FBXO11.

Subcellular location. Nucleus. Chromosome.

Post-translational modifications. Ubiquitinated in a FBXO11-dependent manner; leading to degradation.

Domain organisation. The BAH domain is required for localization at H3K27me3.

Isoforms (3)

UniProt ID	Names	Canonical?
Q8TBE0-1	1	yes
Q8TBE0-2	2
Q8TBE0-3	3

RefSeq proteins (3): NP_001288061, NP_001397973, NP_055767* (*=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR001025	BAH_dom	Domain
IPR043151	BAH_sf	Homologous_superfamily
IPR053032	BAH_domain-containing	Family

Pfam: PF01426

UniProt features (28 total): compositionally biased region 10, modified residue 6, region of interest 5, sequence variant 3, splice variant 2, chain 1, domain 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q8TBE0-F1	51.19	0.12

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (6): 8, 101, 121, 184, 206, 588

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 254 (showing top): MORF_RAGE, GGGACCA_MIR133A_MIR133B, RNGTGGGC_UNKNOWN, RRAGTTGT_UNKNOWN, GCM_GSPT1, TGCACTT_MIR519C_MIR519B_MIR519A, LFA1_Q6, GCANCTGNY_MYOD_Q6, MORF_ATRX, GGGTGGRR_PAX4_03, CAGCTG_AP4_Q5, SP1_Q2_01, CEBPB_01, NFKB_C, GOBP_NEGATIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC

GO Biological Process (3): heterochromatin formation (GO:0031507), negative regulation of DNA-templated transcription (GO:0045892), chromatin organization (GO:0006325)

GO Molecular Function (3): transcription cis-regulatory region binding (GO:0000976), chromatin binding (GO:0003682), protein binding (GO:0005515)

GO Cellular Component (4): nucleoplasm (GO:0005654), chromatin silencing complex (GO:0005677), chromosome (GO:0005694), nucleus (GO:0005634)

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
binding	2
cellular component assembly	1
heterochromatin boundary formation	1
negative regulation of gene expression, epigenetic	1
heterochromatin organization	1
DNA-templated transcription	1
regulation of DNA-templated transcription	1
negative regulation of RNA biosynthetic process	1
cellular component organization	1
transcription regulatory region nucleic acid binding	1
sequence-specific double-stranded DNA binding	1
nuclear lumen	1
cellular anatomical structure	1
nuclear protein-containing complex	1
intracellular membraneless organelle	1
intracellular membrane-bounded organelle	1

Protein interactions and networks

STRING

1084 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
BAHD1	HDAC5	Q9UQL6	684
BAHD1	SETDB1	Q15047	553
BAHD1	MIER1	Q8N108	535
BAHD1	PPP1R35	Q8TAP8	493
BAHD1	MIER3	Q7Z3K6	488
BAHD1	TRIM28	Q13263	474
BAHD1	PDXDC1	Q6P996	441
BAHD1	NAA30	Q147X3	437
BAHD1	MRPL47	Q9HD33	434
BAHD1	PHF20L1	A8MW92	413
BAHD1	FBXL5	Q9UKA1	412
BAHD1	RPUSD2	Q8IZ73	404
BAHD1	PIK3IP1	Q96FE7	400
BAHD1	TATDN2	Q93075	398
BAHD1	TMEM43	Q9BTV4	394

IntAct

244 interactions, top by confidence:

A	B	Type	Score
MDFI	BAHD1	psi-mi:“MI:0915”(physical association)	0.780
BAHD1	LZTS2	psi-mi:“MI:0915”(physical association)	0.780
LZTS2	BAHD1	psi-mi:“MI:0915”(physical association)	0.780
BAHD1	MDFI	psi-mi:“MI:0915”(physical association)	0.780
TRAF4	BAHD1	psi-mi:“MI:0915”(physical association)	0.720
BAHD1	TRAF4	psi-mi:“MI:0915”(physical association)	0.720
KHDRBS3	BAHD1	psi-mi:“MI:0915”(physical association)	0.670
BAHD1	KHDRBS3	psi-mi:“MI:0915”(physical association)	0.670
TRAF2	BAHD1	psi-mi:“MI:0915”(physical association)	0.670
BAHD1	DVL3	psi-mi:“MI:0915”(physical association)	0.670
	BAHD1	psi-mi:“MI:0915”(physical association)	0.560
BAHD1		psi-mi:“MI:0915”(physical association)	0.560
BAHD1	KRTAP10-7	psi-mi:“MI:0915”(physical association)	0.560
TLE5	BAHD1	psi-mi:“MI:0915”(physical association)	0.560
GOLGA2	BAHD1	psi-mi:“MI:0915”(physical association)	0.560
CALCOCO2	BAHD1	psi-mi:“MI:0915”(physical association)	0.560
BAHD1	KRT40	psi-mi:“MI:0915”(physical association)	0.560
KRTAP10-7	BAHD1	psi-mi:“MI:0915”(physical association)	0.560
BAHD1	CALCOCO2	psi-mi:“MI:0915”(physical association)	0.560

BioGRID (83): BAHD1 (Two-hybrid), BAHD1 (Two-hybrid), BAHD1 (Two-hybrid), BAHD1 (Two-hybrid), BAHD1 (Two-hybrid), BAHD1 (Two-hybrid), LZTS2 (Two-hybrid), KRT40 (Two-hybrid), KRTAP10-7 (Two-hybrid), KRTAP10-1 (Two-hybrid), KRTAP10-3 (Two-hybrid), BAHD1 (Affinity Capture-MS), BAHD1 (Two-hybrid), BAHD1 (Two-hybrid), BEGAIN (Two-hybrid)

ESM2 similar proteins: A0JNJ4, A2APT9, A6NEL2, A6NP61, B1ASB6, B1WBS3, B2RXF5, F6WEQ6, O15015, O43918, O88282, O88286, O95785, P98168, P98169, Q2M3G4, Q2MHN3, Q2QGD7, Q3U1J1, Q3U381, Q497V6, Q5SW24, Q5SXM2, Q6YND2, Q6ZMQ8, Q6ZMY3, Q7TN08, Q7TSX9, Q80SU3, Q80YE4, Q811H0, Q8BG26, Q8BZW2, Q8C8V1, Q8IX07, Q8IY92, Q8N143, Q8N1G0, Q8NC74, Q8TBE0

Diamond homologs: O15417, Q3LHL9, Q497V6, Q80WC3, Q8TBE0, F4JGB7, F4JL28, Q3UHR0, Q9FEN9, Q9P281

SIGNOR signaling

0 interactions.

Enriched among interaction partners

Reactome pathways and GO biological processes over-represented among this gene’s 64 IntAct physical interaction partners (hypergeometric vs the genome-wide background, BH-FDR, gene-set size 15–500, ranked by fold). A functional readout of the neighbourhood — distinct from this gene’s own memberships above, and biased toward well-studied / hub proteins, so read it as themes rather than proof.

Reactome pathways:

Pathway	Partners	Fold	FDR
Keratinization	7	8.9×	3e-03

Disease & clinical

Clinical variants and AI predictions

ClinVar

135 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	131
Likely benign	2
Benign	1

Top pathogenic / likely-pathogenic (0)

SpliceAI

939 predictions. Top by Δscore:

Variant	Effect	Δscore
15:40463851:T:TA	acceptor_gain	1.0000
15:40463858:TA:T	acceptor_loss	1.0000
15:40463859:A:AG	acceptor_gain	1.0000
15:40463859:AG:A	acceptor_gain	1.0000
15:40463860:G:GT	acceptor_gain	1.0000
15:40463860:GG:G	acceptor_gain	1.0000
15:40463860:GGAT:G	acceptor_gain	1.0000
15:40464017:TCAGG:T	donor_loss	1.0000
15:40464018:CAG:C	donor_loss	1.0000
15:40464021:G:GA	donor_loss	1.0000
15:40464022:T:G	donor_loss	1.0000
15:40464466:TCCA:T	acceptor_loss	1.0000
15:40464469:A:AG	acceptor_gain	1.0000
15:40464469:AGG:A	acceptor_loss	1.0000
15:40464470:G:GG	acceptor_gain	1.0000
15:40464470:GGA:G	acceptor_gain	1.0000
15:40464547:GGT:G	donor_loss	1.0000
15:40464548:GT:G	donor_loss	1.0000
15:40464549:T:G	donor_loss	1.0000
15:40465331:T:TA	acceptor_gain	1.0000
15:40465333:A:AG	acceptor_gain	1.0000
15:40465334:G:GG	acceptor_gain	1.0000
15:40465432:GCAG:G	donor_gain	1.0000
15:40465433:CAGG:C	donor_loss	1.0000
15:40465436:G:GA	donor_loss	1.0000
15:40465436:G:GG	donor_gain	1.0000
15:40465940:GGTTC:G	acceptor_gain	1.0000
15:40462292:TTGGT:T	donor_loss	0.9900
15:40462293:TGG:T	donor_loss	0.9900
15:40462294:GGT:G	donor_loss	0.9900

AlphaMissense

4977 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
15:40462250:T:A	W591R	1.000
15:40462250:T:C	W591R	1.000
15:40462251:G:C	W591S	1.000
15:40462252:G:C	W591C	1.000
15:40462252:G:T	W591C	1.000
15:40463891:T:G	Y616D	1.000
15:40463933:G:C	D630H	1.000
15:40463934:A:C	D630A	1.000
15:40463934:A:T	D630V	1.000
15:40463940:T:A	V632D	1.000
15:40463943:T:C	L633P	1.000
15:40463946:T:A	L634H	1.000
15:40463946:T:C	L634P	1.000
15:40463985:C:A	A647D	1.000
15:40463989:G:C	K648N	1.000
15:40463989:G:T	K648N	1.000
15:40463991:T:A	I649N	1.000
15:40463991:T:G	I649S	1.000
15:40463996:G:C	A651P	1.000
15:40464000:T:C	L652P	1.000
15:40464002:T:A	W653R	1.000
15:40464002:T:C	W653R	1.000
15:40464003:G:C	W653S	1.000
15:40464004:G:C	W653C	1.000
15:40464004:G:T	W653C	1.000
15:40464485:A:C	S664R	1.000
15:40464487:C:A	S664R	1.000
15:40464487:C:G	S664R	1.000
15:40464489:T:A	L665H	1.000
15:40464489:T:C	L665P	1.000

dbSNP variants (sampled 300 via entrez): RS1000050417 (15:40454025 A>G), RS1000063701 (15:40441912 C>A,G,T), RS1000281142 (15:40437985 G>A), RS1000285592 (15:40450374 T>C), RS1000437327 (15:40455694 C>A,G,T), RS1000482275 (15:40467750 C>G,T), RS1000552674 (15:40437601 C>A), RS1000615673 (15:40439890 G>T), RS1000701201 (15:40467434 G>A,C), RS1000725808 (15:40456468 C>T), RS1000732444 (15:40444732 G>A), RS1000964166 (15:40445659 G>A), RS1000995268 (15:40445937 G>C), RS1000998898 (15:40461357 G>C,T), RS1001085831 (15:40460720 A>C,G)

Disease associations

OMIM: gene MIM:613880 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

6 associations (top):

Study	Trait	p-value
GCST010002_167	Refractive error	3.000000e-11
GCST010242_81	HDL cholesterol levels	2.000000e-08
GCST010725_23	Malaria	2.000000e-06
GCST010725_38	Malaria	3.000000e-06
GCST010725_80	Malaria	7.000000e-06
GCST90002396_631	Mean reticulocyte volume	2.000000e-16

EFO canonical traits (2, from GWAS)

EFO ID	Trait name
EFO:0004612	high density lipoprotein cholesterol measurement
EFO:0010701	mean reticulocyte volume

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

PharmGKB variants

1 variants.

Variant	Genes	Level	Score	#Clin annots	Drugs
rs3803357	BAHD1		0.00	0

CTD chemical–gene interactions

25 total (human), top 25 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
sodium arsenite	decreases expression, affects cotreatment, increases abundance, increases expression	4
Arsenic	decreases expression, decreases methylation, increases abundance, affects cotreatment, increases expression	3
Benzo(a)pyrene	decreases methylation, increases methylation, increases mutagenesis	2
Valproic Acid	decreases methylation, increases expression	2
FR900359	increases phosphorylation	1
dicrotophos	increases expression	1
methylmercuric chloride	increases expression	1
triphenyl phosphate	affects expression	1
manganese chloride	affects cotreatment, increases abundance, increases expression	1
di-n-butylphosphoric acid	affects expression	1
CGP 52608	affects binding, increases reaction	1
2-palmitoylglycerol	increases expression	1
Doxorubicin	decreases expression	1
Manganese	affects cotreatment, increases abundance, increases expression	1
Ouabain	decreases expression	1
Smoke	decreases expression	1
Thiram	increases expression	1
Tobacco Smoke Pollution	increases expression	1
Urethane	increases expression	1
Cyclosporine	increases expression	1
Metals, Heavy	increases abundance, decreases methylation	1
Copper Sulfate	increases expression	1
Lactic Acid	increases expression	1
Acrylamide	increases expression	1
Vitamin K 3	affects expression	1

Cellosaurus cell lines

2 cell lines: 2 cancer cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_D6BH	HyCyte HeLa KO-hBAHD1	Cancer cell line	Female
CVCL_D9YG	Ubigene HeLa BAHD1 KO	Cancer cell line	Female

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.