BASP1-AS1

Summary

BASP1-AS1 (BASP1 antisense RNA 1, HGNC:26609) is a long non-coding RNA gene on chromosome 5p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26609
Approved symbol	BASP1-AS1
Name	BASP1 antisense RNA 1
Location	5p15.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	LOC285696
Ensembl gene	ENSG00000215196
Ensembl biotype	lncRNA
Entrez	285696
RNAcentral	URS000075DA51 — lncRNA, 3316 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 21 — 21 lncRNA

ENST00000399760, ENST00000655365, ENST00000661332, ENST00000665489, ENST00000665653, ENST00000665920, ENST00000667677, ENST00000668327, ENST00000815198, ENST00000815199, ENST00000815200, ENST00000815201, ENST00000815202, ENST00000815203, ENST00000815204, ENST00000815205, ENST00000815206, ENST00000815207, ENST00000815208, ENST00000815209, ENST00000815210

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000399760 — 3 exons

Exon	Start	End
ENSE00001540077	17216077	17217047
ENSE00001705257	17162469	17162565
ENSE00001759783	17130028	17131900

Expression profiles

Bgee: expression breadth ubiquitous, 154 present calls, max score 97.29.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.7340 / max 35.8250, expressed in 154 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
61057	0.3174	95
61056	0.1233	54
61055	0.1151	55
61058	0.0970	31
61054	0.0812	26

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	97.29	gold quality
cortical plate	UBERON:0005343	85.80	gold quality
ventricular zone	UBERON:0003053	84.75	gold quality
prefrontal cortex	UBERON:0000451	80.64	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.21	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.19	gold quality
ganglionic eminence	UBERON:0004023	80.04	gold quality
right frontal lobe	UBERON:0002810	78.05	gold quality
sural nerve	UBERON:0015488	77.97	gold quality
Brodmann (1909) area 9	UBERON:0013540	77.76	gold quality
anterior cingulate cortex	UBERON:0009835	77.22	gold quality
neocortex	UBERON:0001950	73.73	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	73.70	gold quality
frontal cortex	UBERON:0001870	73.21	gold quality
stromal cell of endometrium	CL:0002255	70.17	gold quality
amygdala	UBERON:0001876	70.02	gold quality
tendon of biceps brachii	UBERON:0008188	69.36	gold quality
cerebral cortex	UBERON:0000956	69.25	gold quality
bone marrow cell	CL:0002092	69.09	silver quality
hypothalamus	UBERON:0001898	68.86	gold quality
cerebellar cortex	UBERON:0002129	66.98	gold quality
cerebellar hemisphere	UBERON:0002245	66.96	gold quality
nucleus accumbens	UBERON:0001882	66.47	gold quality
right hemisphere of cerebellum	UBERON:0014890	66.08	gold quality
cerebellum	UBERON:0002037	65.21	gold quality
forebrain	UBERON:0001890	64.97	gold quality
blood	UBERON:0000178	64.58	gold quality
brain	UBERON:0000955	64.50	gold quality
Ammon’s horn	UBERON:0001954	63.05	gold quality
primary visual cortex	UBERON:0002436	61.88	gold quality

Single-cell (SCXA)

Detected in 3 experiment(s), a significant marker in 3.

Experiment	Marker?	Max mean expression
E-HCAD-30	yes	249.71
E-HCAD-35	yes	59.51
E-ANND-3	yes	3.44

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LncRNA BASP1-AS1 interacts with YBX1 to regulate Notch transcription and drives the malignancy of melanoma. (PMID:34533860)
• LncRNA BASP1-AS1 is a positive regulator of stemness and pluripotency in human SH-SY5Y neuroblastoma cells. (PMID:39303525)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.