BLACE

Summary

BLACE (B cell acute lymphoblastic leukemia expressed, HGNC:20484) is a long non-coding RNA gene on chromosome 7q36.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:20484
Approved symbol	BLACE
Name	B cell acute lymphoblastic leukemia expressed
Location	7q36.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000204960
Ensembl biotype	lncRNA
OMIM	608450
Entrez	338436
RNAcentral	URS000075DC13 — lncRNA, 2469 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000378120

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000378120 — 6 exons

Exon	Start	End
ENSE00001552014	155367809	155367934
ENSE00001562867	155356985	155358780
ENSE00001563399	155362812	155362950
ENSE00001563971	155359900	155360043
ENSE00001564146	155360928	155361084
ENSE00001669257	155363104	155363197

Expression profiles

Bgee: expression breadth tissue_specific, 10 present calls, max score 86.65.

Top tissues by expression

10 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pancreas	UBERON:0001264	86.65	gold quality
muscle tissue	UBERON:0002385	69.68	gold quality
testis	UBERON:0000473	62.88	silver quality
bone marrow	UBERON:0002371	60.86	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	57.20	gold quality
blood	UBERON:0000178	57.00	gold quality
right uterine tube	UBERON:0001302	48.36	gold quality
Ammon’s horn	UBERON:0001954	46.13	silver quality
substantia nigra	UBERON:0002038	35.75	silver quality
left testis	UBERON:0004533	32.73	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.62

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• BLACE is located in region 7q36 and significant expression of BLACE was detected by RT-PCR in bone marrow samples from B cell acute lymphoblastic leukemia patients. (PMID:14667812)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.