BLK-AS1
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Summary
BLK-AS1 (BLK antisense RNA 1, HGNC:58190) is a long non-coding RNA gene on chromosome 8p23.1.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:58190 |
| Approved symbol | BLK-AS1 |
| Name | BLK antisense RNA 1 |
| Location | 8p23.1 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000269954 |
| Ensembl biotype | lncRNA |
| Entrez | 105379241 |
| RNAcentral | URS0000D5FC68 — lncRNA, 1789 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 3 — 3 lncRNA
ENST00000528629, ENST00000533322, ENST00000602626
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000528629 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002157380 | 11556251 | 11556661 |
| ENSE00002157544 | 11557890 | 11558022 |
Expression profiles
Bgee: expression breadth ubiquitous, 124 present calls, max score 97.02.
Top tissues by expression
124 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 97.02 | gold quality |
| lymph node | UBERON:0000029 | 94.71 | gold quality |
| spleen | UBERON:0002106 | 93.29 | gold quality |
| vermiform appendix | UBERON:0001154 | 85.84 | gold quality |
| tonsil | UBERON:0002372 | 85.64 | gold quality |
| granulocyte | CL:0000094 | 84.64 | gold quality |
| small intestine Peyer’s patch | UBERON:0003454 | 81.63 | gold quality |
| blood | UBERON:0000178 | 80.99 | gold quality |
| stromal cell of endometrium | CL:0002255 | 80.70 | gold quality |
| small intestine | UBERON:0002108 | 79.56 | gold quality |
| bone marrow | UBERON:0002371 | 76.65 | gold quality |
| colonic epithelium | UBERON:0000397 | 76.31 | gold quality |
| bone marrow cell | CL:0002092 | 75.55 | gold quality |
| mucosa of transverse colon | UBERON:0004991 | 67.77 | gold quality |
| rectum | UBERON:0001052 | 67.68 | gold quality |
| gall bladder | UBERON:0002110 | 66.88 | gold quality |
| intestine | UBERON:0000160 | 65.46 | gold quality |
| leukocyte | CL:0000738 | 64.88 | gold quality |
| monocyte | CL:0000576 | 63.63 | gold quality |
| transverse colon | UBERON:0001157 | 63.59 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 63.45 | gold quality |
| right lobe of liver | UBERON:0001114 | 61.89 | gold quality |
| esophagus mucosa | UBERON:0002469 | 61.81 | gold quality |
| body of stomach | UBERON:0001161 | 61.61 | gold quality |
| liver | UBERON:0002107 | 61.39 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 61.30 | gold quality |
| olfactory segment of nasal mucosa | UBERON:0005386 | 61.28 | gold quality |
| fundus of stomach | UBERON:0001160 | 61.08 | gold quality |
| stomach | UBERON:0000945 | 60.96 | gold quality |
| urinary bladder | UBERON:0001255 | 60.67 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | yes | 6.18 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): maturity-onset diabetes of the young type 11, monogenic diabetes