BNC2-AS1

Summary

BNC2-AS1 (BNC2 antisense RNA 1, HGNC:53727) is a long non-coding RNA gene on chromosome 9p22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53727
Approved symbol	BNC2-AS1
Name	BNC2 antisense RNA 1
Location	9p22.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-62F24.2
Ensembl gene	ENSG00000234779
Ensembl biotype	lncRNA
Entrez	111216284
RNAcentral	URS000009CB55 — lncRNA, 428 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000450445, ENST00000756362

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000450445 — 3 exons

Exon	Start	End
ENSE00001657349	16726814	16726955
ENSE00001713019	16727315	16727524
ENSE00001770646	16727031	16727106

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 96.27.

FANTOM5 (CAGE): breadth broad, TPM avg 1.2047 / max 29.6996, expressed in 620 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
96188	0.5209	333
96189	0.2739	146
96190	0.2405	100
96191	0.1694	97

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.27	gold quality
left ovary	UBERON:0002119	83.80	gold quality
ovary	UBERON:0000992	82.13	gold quality
right uterine tube	UBERON:0001302	81.23	gold quality
right ovary	UBERON:0002118	81.23	gold quality
left uterine tube	UBERON:0001303	79.41	gold quality
body of uterus	UBERON:0009853	76.00	gold quality
tibial nerve	UBERON:0001323	75.55	gold quality
myometrium	UBERON:0001296	75.07	gold quality
fallopian tube	UBERON:0003889	74.78	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.58	gold quality
endocervix	UBERON:0000458	74.31	gold quality
colonic epithelium	UBERON:0000397	73.77	gold quality
uterine cervix	UBERON:0000002	72.78	gold quality
sural nerve	UBERON:0015488	72.34	gold quality
muscle layer of sigmoid colon	UBERON:0035805	72.17	gold quality
subcutaneous adipose tissue	UBERON:0002190	72.13	gold quality
adipose tissue	UBERON:0001013	71.80	gold quality
calcaneal tendon	UBERON:0003701	71.48	gold quality
omental fat pad	UBERON:0010414	71.48	gold quality
ectocervix	UBERON:0012249	71.21	gold quality
urinary bladder	UBERON:0001255	70.81	gold quality
adult mammalian kidney	UBERON:0000082	70.56	gold quality
left coronary artery	UBERON:0001626	70.37	gold quality
mucosa of stomach	UBERON:0001199	69.61	gold quality
apex of heart	UBERON:0002098	68.91	gold quality
gall bladder	UBERON:0002110	68.71	gold quality
kidney	UBERON:0002113	68.62	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	68.62	gold quality
vagina	UBERON:0000996	68.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.08

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long non-coding RNA (lncRNA) BNC2-AS1 (BNC2-AS1) knockdown can significantly suppress the tumor characteristics of gastric cancer cells, including the ability of proliferation, migration, and invasion. (PMID:30549996)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.