BOK-AS1

Summary

BOK-AS1 (BOK antisense RNA 1, HGNC:35125) is a long non-coding RNA gene on chromosome 2q37.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:35125
Approved symbol	BOK-AS1
Name	BOK antisense RNA 1
Location	2q37.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	NCRNA00151, NAToB
Ensembl gene	ENSG00000234235
Ensembl biotype	lncRNA
Entrez	100379249
RNAcentral	URS000017AD75 — lncRNA, 849 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000434306, ENST00000758668, ENST00000758669, ENST00000758670, ENST00000758671, ENST00000758672, ENST00000758673, ENST00000758674, ENST00000758675, ENST00000758676, ENST00000758677, ENST00000758678, ENST00000758679, ENST00000758680, ENST00000758681, ENST00000758682, ENST00000758683

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434306 — 2 exons

Exon	Start	End
ENSE00001626631	241558777	241558977
ENSE00001637082	241544403	241544844

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 69.85.

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.85	gold quality
liver	UBERON:0002107	66.18	gold quality
right lobe of liver	UBERON:0001114	65.99	gold quality
skeletal muscle tissue	UBERON:0001134	65.88	silver quality
bone marrow cell	CL:0002092	65.58	silver quality
sural nerve	UBERON:0015488	63.57	silver quality
cortical plate	UBERON:0005343	63.54	gold quality
ganglionic eminence	UBERON:0004023	61.72	gold quality
lymph node	UBERON:0000029	59.41	gold quality
subcutaneous adipose tissue	UBERON:0002190	58.00	gold quality
stromal cell of endometrium	CL:0002255	57.79	gold quality
placenta	UBERON:0001987	57.27	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.63	gold quality
adipose tissue	UBERON:0001013	56.53	gold quality
prefrontal cortex	UBERON:0000451	55.75	gold quality
primary visual cortex	UBERON:0002436	55.35	gold quality
urinary bladder	UBERON:0001255	54.89	gold quality
thoracic mammary gland	UBERON:0005200	54.65	gold quality
cerebellum	UBERON:0002037	54.25	gold quality
cerebellar cortex	UBERON:0002129	54.18	gold quality
omental fat pad	UBERON:0010414	54.05	gold quality
cerebellar hemisphere	UBERON:0002245	53.99	gold quality
monocyte	CL:0000576	53.29	gold quality
calcaneal tendon	UBERON:0003701	52.80	silver quality
right hemisphere of cerebellum	UBERON:0014890	52.71	gold quality
kidney	UBERON:0002113	50.88	gold quality
islet of Langerhans	UBERON:0000006	50.78	gold quality
granulocyte	CL:0000094	50.71	silver quality
gall bladder	UBERON:0002110	50.42	gold quality
blood	UBERON:0000178	50.40	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Up-regulation of BOK-AS1, FAM215A and FEZF1-AS1 lncRNAs and their potency as moderate diagnostic biomarkers in gastric cancer. (PMID:37364417)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.