BOLA3-DT

Summary

BOLA3-DT (BOLA3 divergent transcript, HGNC:42922) is a long non-coding RNA gene on chromosome 2p13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42922
Approved symbol	BOLA3-DT
Name	BOLA3 divergent transcript
Location	2p13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225439
Ensembl biotype	lncRNA
Entrez	100507171
RNAcentral	URS000075DD81 — lncRNA, 4190 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000423477, ENST00000529783, ENST00000533563, ENST00000655044, ENST00000656407, ENST00000691938, ENST00000803106, ENST00000803107, ENST00000803108, ENST00000803109, ENST00000803110, ENST00000803111

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000423477 — 2 exons

Exon	Start	End
ENSE00001690053	74148039	74148478
ENSE00001789415	74148698	74150061

Expression profiles

Bgee: expression breadth ubiquitous, 171 present calls, max score 89.15.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.5894 / max 85.3909, expressed in 1230 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
21008	1.3958	697
21009	1.3760	806
21010	0.6266	328
21007	0.1910	74

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	89.15	gold quality
ganglionic eminence	UBERON:0004023	80.60	gold quality
ventricular zone	UBERON:0003053	80.54	gold quality
prefrontal cortex	UBERON:0000451	80.19	gold quality
anterior cingulate cortex	UBERON:0009835	78.64	gold quality
Brodmann (1909) area 9	UBERON:0013540	78.44	gold quality
cerebellar hemisphere	UBERON:0002245	77.86	gold quality
cerebellar cortex	UBERON:0002129	77.84	gold quality
cerebellum	UBERON:0002037	77.27	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	77.20	gold quality
right hemisphere of cerebellum	UBERON:0014890	77.19	gold quality
right frontal lobe	UBERON:0002810	77.06	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	76.85	gold quality
neocortex	UBERON:0001950	76.48	gold quality
frontal cortex	UBERON:0001870	76.03	gold quality
hypothalamus	UBERON:0001898	75.89	gold quality
islet of Langerhans	UBERON:0000006	75.83	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.48	gold quality
spinal cord	UBERON:0002240	75.20	gold quality
nucleus accumbens	UBERON:0001882	75.08	gold quality
descending thoracic aorta	UBERON:0002345	74.72	gold quality
smooth muscle tissue	UBERON:0001135	74.37	gold quality
caudate nucleus	UBERON:0001873	74.17	gold quality
popliteal artery	UBERON:0002250	74.15	gold quality
tibial artery	UBERON:0007610	74.13	gold quality
thoracic aorta	UBERON:0001515	74.08	gold quality
cerebral cortex	UBERON:0000956	74.07	gold quality
aorta	UBERON:0000947	74.01	gold quality
ascending aorta	UBERON:0001496	73.93	gold quality
putamen	UBERON:0001874	73.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.16

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.