BRWD1-IT1

Summary

BRWD1-IT1 (BRWD1 intronic transcript 1, HGNC:41920) is a long non-coding RNA gene on chromosome 21q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41920
Approved symbol	BRWD1-IT1
Name	BRWD1 intronic transcript 1
Location	21q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237373
Ensembl biotype	lncRNA
Entrez	106480743
RNAcentral	URS0000347CF6 — lncRNA, 489 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000435608

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435608 — 2 exons

Exon	Start	End
ENSE00001635289	39217093	39217177
ENSE00001651259	39219402	39219805

Expression profiles

Bgee: expression breadth ubiquitous, 110 present calls, max score 82.39.

Top tissues by expression

110 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.39	silver quality
colonic epithelium	UBERON:0000397	70.45	gold quality
tonsil	UBERON:0002372	67.39	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.08	gold quality
skeletal muscle tissue	UBERON:0001134	63.86	silver quality
duodenum	UBERON:0002114	62.70	gold quality
sural nerve	UBERON:0015488	62.40	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	62.06	gold quality
urinary bladder	UBERON:0001255	61.57	gold quality
bone marrow cell	CL:0002092	61.18	silver quality
adrenal tissue	UBERON:0018303	60.41	gold quality
kidney	UBERON:0002113	58.73	gold quality
liver	UBERON:0002107	58.61	gold quality
calcaneal tendon	UBERON:0003701	58.07	gold quality
stromal cell of endometrium	CL:0002255	57.12	gold quality
blood	UBERON:0000178	56.28	gold quality
islet of Langerhans	UBERON:0000006	55.95	gold quality
adult mammalian kidney	UBERON:0000082	55.21	gold quality
superior frontal gyrus	UBERON:0002661	54.99	gold quality
vermiform appendix	UBERON:0001154	53.60	gold quality
placenta	UBERON:0001987	53.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.21	gold quality
primary visual cortex	UBERON:0002436	53.08	gold quality
endometrium	UBERON:0001295	52.53	silver quality
muscle of leg	UBERON:0001383	52.22	gold quality
monocyte	CL:0000576	51.81	silver quality
pancreas	UBERON:0001264	50.44	gold quality
myometrium	UBERON:0001296	50.29	gold quality
stomach	UBERON:0000945	50.04	gold quality
uterine cervix	UBERON:0000002	50.02	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.