BTG2-DT

Summary

BTG2-DT (BTG2 divergent transcript, HGNC:49452) is a long non-coding RNA gene on chromosome 1q32.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49452
Approved symbol	BTG2-DT
Name	BTG2 divergent transcript
Location	1q32.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233791
Ensembl biotype	lncRNA
Entrez	730227
RNAcentral	URS000075AC38 — lncRNA, 2555 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 30 — 30 lncRNA

ENST00000425698, ENST00000432511, ENST00000457348, ENST00000688684, ENST00000689090, ENST00000689493, ENST00000690477, ENST00000691117, ENST00000778939, ENST00000778940, ENST00000778941, ENST00000778942, ENST00000778943, ENST00000778944, ENST00000778945, ENST00000778946, ENST00000778947, ENST00000778948, ENST00000778949, ENST00000778950, ENST00000778951, ENST00000778952, ENST00000778953, ENST00000778954, ENST00000778955, ENST00000778956, ENST00000778957, ENST00000778958, ENST00000778959, ENST00000778960

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425698 — 4 exons

Exon	Start	End
ENSE00001637363	203300514	203300647
ENSE00001777940	203301090	203301281
ENSE00001782679	203304520	203304630
ENSE00004148907	203305057	203305361

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 75.55.

FANTOM5 (CAGE): breadth broad, TPM avg 3.8371 / max 592.4444, expressed in 625 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
16823	2.1546	539
16819	0.5857	92
16822	0.5064	188
16818	0.2459	49
16821	0.1981	93
16820	0.1464	52

Top tissues by expression

271 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.55	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.91	gold quality
granulocyte	CL:0000094	70.12	gold quality
pancreatic ductal cell	CL:0002079	69.59	silver quality
ileal mucosa	UBERON:0000331	68.21	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.14	gold quality
skin of abdomen	UBERON:0001416	67.13	gold quality
colonic epithelium	UBERON:0000397	66.93	silver quality
tibialis anterior	UBERON:0001385	65.20	silver quality
bone marrow cell	CL:0002092	65.11	silver quality
ganglionic eminence	UBERON:0004023	64.89	gold quality
blood	UBERON:0000178	63.68	gold quality
cervix squamous epithelium	UBERON:0006922	63.48	gold quality
vermiform appendix	UBERON:0001154	63.00	gold quality
skin of leg	UBERON:0001511	62.40	gold quality
body of pancreas	UBERON:0001150	61.82	gold quality
zone of skin	UBERON:0000014	61.64	gold quality
muscle of leg	UBERON:0001383	60.00	gold quality
pancreas	UBERON:0001264	59.85	gold quality
gastrocnemius	UBERON:0001388	59.69	gold quality
leukocyte	CL:0000738	59.29	gold quality
monocyte	CL:0000576	58.91	gold quality
mononuclear cell	CL:0000842	58.80	gold quality
ventricular zone	UBERON:0003053	58.24	silver quality
caecum	UBERON:0001153	57.53	gold quality
muscle organ	UBERON:0001630	56.82	gold quality
gall bladder	UBERON:0002110	56.68	gold quality
smooth muscle tissue	UBERON:0001135	56.47	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.31	gold quality
skin of hip	UBERON:0001554	56.03	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.