BTG3-AS1

Summary

BTG3-AS1 (BTG3 antisense RNA 1, HGNC:53145) is a long non-coding RNA gene on chromosome 21q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53145
Approved symbol	BTG3-AS1
Name	BTG3 antisense RNA 1
Location	21q21.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	ASBEL
Ensembl gene	ENSG00000280594
Ensembl biotype	lncRNA
Entrez	110806272
RNAcentral	URS0000BC43C1 — lncRNA, 2435 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 4 lncRNA, 1 retained_intron

ENST00000626994, ENST00000630155, ENST00000690626, ENST00000701920, ENST00000807308

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000626994 — 3 exons

Exon	Start	End
ENSE00003773426	17626893	17627049
ENSE00003773795	17611744	17612087
ENSE00003774205	17633149	17633199

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 81.76.

FANTOM5 (CAGE): breadth broad, TPM avg 1.6789 / max 28.7448, expressed in 779 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
188585	1.6789	779

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.76	gold quality
ventricular zone	UBERON:0003053	78.85	gold quality
bone marrow cell	CL:0002092	74.45	gold quality
ganglionic eminence	UBERON:0004023	73.74	gold quality
islet of Langerhans	UBERON:0000006	70.80	gold quality
stromal cell of endometrium	CL:0002255	68.42	gold quality
colonic epithelium	UBERON:0000397	67.96	silver quality
endometrium	UBERON:0001295	67.67	gold quality
bone marrow	UBERON:0002371	67.52	gold quality
body of uterus	UBERON:0009853	66.20	gold quality
rectum	UBERON:0001052	65.74	gold quality
myometrium	UBERON:0001296	64.47	gold quality
cortical plate	UBERON:0005343	64.32	gold quality
mucosa of transverse colon	UBERON:0004991	64.19	gold quality
fallopian tube	UBERON:0003889	64.10	gold quality
tonsil	UBERON:0002372	63.07	gold quality
sural nerve	UBERON:0015488	62.76	gold quality
calcaneal tendon	UBERON:0003701	62.39	gold quality
placenta	UBERON:0001987	62.09	gold quality
uterine cervix	UBERON:0000002	61.95	gold quality
ectocervix	UBERON:0012249	61.57	gold quality
adrenal tissue	UBERON:0018303	61.10	gold quality
vagina	UBERON:0000996	60.97	gold quality
right testis	UBERON:0004534	60.89	gold quality
smooth muscle tissue	UBERON:0001135	60.83	gold quality
muscle layer of sigmoid colon	UBERON:0035805	60.74	gold quality
testis	UBERON:0000473	60.35	gold quality
adenohypophysis	UBERON:0002196	60.32	gold quality
endocervix	UBERON:0000458	60.26	gold quality
skin of abdomen	UBERON:0001416	60.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.70

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.