C12orf75-AS1

Summary

C12orf75-AS1 (C12orf75 antisense RNA 1, HGNC:55936) is a long non-coding RNA gene on chromosome 12q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55936
Approved symbol	C12orf75-AS1
Name	C12orf75 antisense RNA 1
Location	12q23.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	KCCAT198
Ensembl gene	ENSG00000257642
Ensembl biotype	lncRNA
Entrez	105369954
RNAcentral	URS00001962CC — lncRNA, 549 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000549251

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000549251 — 3 exons

Exon	Start	End
ENSE00002326299	105326904	105327017
ENSE00002351999	105308629	105308780
ENSE00002374186	105304867	105305149

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 85.36.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4091 / max 43.4305, expressed in 176 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
133035	0.4091	176

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.36	gold quality
sural nerve	UBERON:0015488	73.56	silver quality
endometrium	UBERON:0001295	73.14	gold quality
endocervix	UBERON:0000458	69.34	gold quality
ventricular zone	UBERON:0003053	65.81	gold quality
cortical plate	UBERON:0005343	65.00	gold quality
cortex of kidney	UBERON:0001225	61.58	gold quality
skeletal muscle tissue	UBERON:0001134	61.34	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.03	gold quality
stromal cell of endometrium	CL:0002255	59.81	gold quality
adult mammalian kidney	UBERON:0000082	59.64	gold quality
kidney	UBERON:0002113	58.81	gold quality
granulocyte	CL:0000094	58.02	gold quality
ganglionic eminence	UBERON:0004023	56.67	silver quality
lymph node	UBERON:0000029	56.34	gold quality
islet of Langerhans	UBERON:0000006	56.27	gold quality
right uterine tube	UBERON:0001302	55.37	gold quality
prefrontal cortex	UBERON:0000451	55.33	gold quality
placenta	UBERON:0001987	55.15	gold quality
metanephros cortex	UBERON:0010533	54.98	gold quality
leukocyte	CL:0000738	54.72	gold quality
monocyte	CL:0000576	53.69	gold quality
blood	UBERON:0000178	53.69	gold quality
calcaneal tendon	UBERON:0003701	53.41	gold quality
liver	UBERON:0002107	52.87	gold quality
lower esophagus mucosa	UBERON:0035834	52.71	gold quality
superior frontal gyrus	UBERON:0002661	51.98	gold quality
vermiform appendix	UBERON:0001154	51.55	gold quality
right lobe of liver	UBERON:0001114	51.47	gold quality
descending thoracic aorta	UBERON:0002345	51.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.