C16orf46-DT

Summary

C16orf46-DT (C16orf46 divergent transcript, HGNC:56680) is a long non-coding RNA gene on chromosome 16q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56680
Approved symbol	C16orf46-DT
Name	C16orf46 divergent transcript
Location	16q23.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	lnc-ATMIN-4:2
Ensembl gene	ENSG00000245059
Ensembl biotype	lncRNA
Entrez	128266836
RNAcentral	URS000010E2CC — lncRNA, 1088 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000501068

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501068 — 2 exons

Exon	Start	End
ENSE00001976225	81078332	81078861
ENSE00001980679	81077319	81077876

Expression profiles

Bgee: expression breadth broad, 92 present calls, max score 78.91.

Top tissues by expression

191 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.91	silver quality
sural nerve	UBERON:0015488	62.80	silver quality
colonic epithelium	UBERON:0000397	60.44	silver quality
cortical plate	UBERON:0005343	55.45	silver quality
lower lobe of lung	UBERON:0008949	53.53	silver quality
monocyte	CL:0000576	51.94	silver quality
sperm	CL:0000019	50.70	gold quality
prefrontal cortex	UBERON:0000451	49.98	silver quality
calcaneal tendon	UBERON:0003701	49.80	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	47.98	gold quality
muscle of leg	UBERON:0001383	47.72	silver quality
islet of Langerhans	UBERON:0000006	47.47	gold quality
gall bladder	UBERON:0002110	47.11	gold quality
vermiform appendix	UBERON:0001154	46.97	silver quality
right lobe of liver	UBERON:0001114	46.81	gold quality
left testis	UBERON:0004533	46.61	gold quality
skin of hip	UBERON:0001554	46.54	gold quality
testis	UBERON:0000473	46.10	gold quality
gastrocnemius	UBERON:0001388	45.98	gold quality
pancreas	UBERON:0001264	45.94	silver quality
left lobe of thyroid gland	UBERON:0001120	45.79	gold quality
body of pancreas	UBERON:0001150	45.55	silver quality
thyroid gland	UBERON:0002046	45.43	gold quality
right testis	UBERON:0004534	45.39	gold quality
smooth muscle tissue	UBERON:0001135	44.95	silver quality
liver	UBERON:0002107	44.74	silver quality
upper lobe of lung	UBERON:0008948	44.65	silver quality
apex of heart	UBERON:0002098	44.45	silver quality
right lobe of thyroid gland	UBERON:0001119	44.13	gold quality
frontal cortex	UBERON:0001870	43.71	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.26

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Identification of a Novel Long Non-coding RNA, lnc-ATMIN-4:2, and its Clinicopathological and Prognostic Significance in Advanced Gastric Cancer. (PMID:36316044)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.