C2-AS1

Summary

C2-AS1 (C2 antisense RNA 1, HGNC:49464) is a long non-coding RNA gene on chromosome 6p21.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49464
Approved symbol	C2-AS1
Name	C2 antisense RNA 1
Location	6p21.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000281756
Ensembl biotype	lncRNA
Entrez	102060414
RNAcentral	URS000075D5AD — lncRNA, 762 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000630806, ENST00000817243

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000630806 — 3 exons

Exon	Start	End
ENSE00003760812	31941185	31941724
ENSE00003771314	31934474	31934632
ENSE00003772637	31935340	31935402

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 79.47.

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.47	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.44	silver quality
right lobe of liver	UBERON:0001114	76.47	gold quality
liver	UBERON:0002107	73.04	gold quality
cortical plate	UBERON:0005343	66.76	gold quality
skeletal muscle tissue	UBERON:0001134	61.03	gold quality
upper lobe of left lung	UBERON:0008952	60.50	gold quality
lung	UBERON:0002048	59.60	gold quality
right lung	UBERON:0002167	58.69	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.05	gold quality
vermiform appendix	UBERON:0001154	57.02	gold quality
spleen	UBERON:0002106	56.34	gold quality
calcaneal tendon	UBERON:0003701	56.09	silver quality
muscle tissue	UBERON:0002385	55.58	gold quality
omental fat pad	UBERON:0010414	55.12	gold quality
monocyte	CL:0000576	55.03	gold quality
bone marrow	UBERON:0002371	55.02	gold quality
granulocyte	CL:0000094	54.41	gold quality
lymph node	UBERON:0000029	53.84	gold quality
placenta	UBERON:0001987	53.72	gold quality
adipose tissue	UBERON:0001013	53.46	gold quality
duodenum	UBERON:0002114	53.10	gold quality
gall bladder	UBERON:0002110	52.27	gold quality
small intestine	UBERON:0002108	52.24	gold quality
smooth muscle tissue	UBERON:0001135	52.22	gold quality
endometrium	UBERON:0001295	52.22	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.22	gold quality
blood	UBERON:0000178	52.12	silver quality
subcutaneous adipose tissue	UBERON:0002190	52.04	gold quality
small intestine Peyer’s patch	UBERON:0003454	51.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.