C2orf49-DT

Summary

C2orf49-DT (C2orf49 divergent transcript, HGNC:55178) is a long non-coding RNA gene on chromosome 2q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55178
Approved symbol	C2orf49-DT
Name	C2orf49 divergent transcript
Location	2q12.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272994
Ensembl biotype	lncRNA
Entrez	100506473
RNAcentral	URS00026A1CEF — lncRNA, 5875 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000610036, ENST00000729450, ENST00000729451

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000610036 — 1 exons

Exon	Start	End
ENSE00003987809	105333935	105337509

Expression profiles

Bgee: expression breadth ubiquitous, 204 present calls, max score 85.86.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.2227 / max 48.7986, expressed in 991 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
30022	2.2227	991

Top tissues by expression

243 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cardiac muscle of right atrium	UBERON:0003379	85.86	gold quality
left ventricle myocardium	UBERON:0006566	85.84	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.47	gold quality
ileal mucosa	UBERON:0000331	78.34	silver quality
myocardium	UBERON:0002349	78.32	gold quality
buccal mucosa cell	CL:0002336	75.04	gold quality
epithelial cell of pancreas	CL:0000083	74.46	silver quality
kidney epithelium	UBERON:0004819	73.22	gold quality
pancreatic ductal cell	CL:0002079	71.52	silver quality
right uterine tube	UBERON:0001302	71.40	gold quality
left ovary	UBERON:0002119	71.36	gold quality
tibialis anterior	UBERON:0001385	71.29	silver quality
granulocyte	CL:0000094	70.28	gold quality
cerebellar vermis	UBERON:0004720	70.22	gold quality
right ovary	UBERON:0002118	69.85	gold quality
left lobe of thyroid gland	UBERON:0001120	69.56	gold quality
nasal cavity epithelium	UBERON:0005384	69.56	gold quality
lower lobe of lung	UBERON:0008949	69.12	silver quality
tibia	UBERON:0000979	69.10	gold quality
thyroid gland	UBERON:0002046	68.98	gold quality
right lobe of thyroid gland	UBERON:0001119	68.87	gold quality
pigmented layer of retina	UBERON:0001782	68.77	gold quality
ovary	UBERON:0000992	68.74	gold quality
colonic epithelium	UBERON:0000397	68.59	silver quality
ganglionic eminence	UBERON:0004023	68.57	gold quality
cerebellar cortex	UBERON:0002129	68.47	gold quality
cerebellar hemisphere	UBERON:0002245	68.47	gold quality
ventricular zone	UBERON:0003053	68.06	gold quality
cerebellum	UBERON:0002037	68.03	gold quality
right hemisphere of cerebellum	UBERON:0014890	67.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.