C2orf74-AS1

Summary

C2orf74-AS1 (C2orf74 antisense RNA 1, HGNC:56377) is a long non-coding RNA gene on chromosome 2p15.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56377
Approved symbol	C2orf74-AS1
Name	C2orf74 antisense RNA 1
Location	2p15
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC016747.2
Ensembl gene	ENSG00000271889
Ensembl biotype	lncRNA
Entrez	105374758
RNAcentral	URS00026A269E — lncRNA, 379 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000417691, ENST00000420918, ENST00000422740, ENST00000443946, ENST00000605902, ENST00000606876, ENST00000607743, ENST00000715767, ENST00000733741, ENST00000733742, ENST00000733743, ENST00000733744, ENST00000733745, ENST00000733746, ENST00000733747, ENST00000733748

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417691 — 2 exons

Exon	Start	End
ENSE00004065258	61144773	61144980
ENSE00004065259	61143543	61144266

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 96.29.

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	96.29	gold quality
testis	UBERON:0000473	95.80	gold quality
right testis	UBERON:0004534	95.56	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.16	gold quality
cortical plate	UBERON:0005343	85.30	gold quality
sural nerve	UBERON:0015488	82.71	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.96	gold quality
corpus callosum	UBERON:0002336	80.80	gold quality
endometrium	UBERON:0001295	74.84	gold quality
right uterine tube	UBERON:0001302	74.29	gold quality
cortex of kidney	UBERON:0001225	72.70	gold quality
body of pancreas	UBERON:0001150	71.97	gold quality
right lobe of liver	UBERON:0001114	71.77	gold quality
metanephros cortex	UBERON:0010533	71.08	gold quality
right adrenal gland	UBERON:0001233	70.83	gold quality
lymph node	UBERON:0000029	70.24	gold quality
right lobe of thyroid gland	UBERON:0001119	70.15	gold quality
adrenal tissue	UBERON:0018303	70.00	gold quality
pituitary gland	UBERON:0000007	69.95	gold quality
apex of heart	UBERON:0002098	69.78	gold quality
pancreas	UBERON:0001264	69.74	gold quality
gall bladder	UBERON:0002110	69.52	gold quality
spleen	UBERON:0002106	69.50	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.48	gold quality
right adrenal gland cortex	UBERON:0035827	69.34	gold quality
liver	UBERON:0002107	69.23	gold quality
skeletal muscle tissue	UBERON:0001134	69.13	gold quality
left ovary	UBERON:0002119	68.54	gold quality
fundus of stomach	UBERON:0001160	68.41	gold quality
ovary	UBERON:0000992	68.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.