C8orf34-AS1

Summary

C8orf34-AS1 (C8orf34 antisense RNA 1, HGNC:27840) is a long non-coding RNA gene on chromosome 8q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27840
Approved symbol	C8orf34-AS1
Name	C8orf34 antisense RNA 1
Location	8q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248801
Ensembl biotype	lncRNA
Entrez	286189
RNAcentral	URS000075EA23 — lncRNA, 1630 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000512294, ENST00000584858, ENST00000653063, ENST00000653785, ENST00000656279, ENST00000656712, ENST00000659515, ENST00000659689, ENST00000660308, ENST00000666602

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000512294 — 4 exons

Exon	Start	End
ENSE00002035169	68303506	68304801
ENSE00003756897	68306518	68306598
ENSE00003874954	68308860	68308963
ENSE00003877691	68331307	68331509

Expression profiles

Bgee: expression breadth ubiquitous, 155 present calls, max score 84.40.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2043 / max 24.0783, expressed in 96 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
93457	0.1029	56
93458	0.0610	28
93459	0.0403	17

Top tissues by expression

232 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	84.40	gold quality
right uterine tube	UBERON:0001302	80.57	gold quality
oviduct epithelium	UBERON:0004804	79.66	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.86	silver quality
lower lobe of lung	UBERON:0008949	75.51	gold quality
cerebellar cortex	UBERON:0002129	73.75	gold quality
cerebellar hemisphere	UBERON:0002245	73.73	gold quality
endothelial cell	CL:0000115	73.39	silver quality
upper lobe of lung	UBERON:0008948	73.00	gold quality
upper lobe of left lung	UBERON:0008952	72.81	gold quality
body of pancreas	UBERON:0001150	72.44	gold quality
cerebellum	UBERON:0002037	72.14	gold quality
bronchial epithelial cell	CL:0002328	72.10	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.60	gold quality
right lung	UBERON:0002167	71.20	gold quality
bronchus	UBERON:0002185	70.67	gold quality
colonic epithelium	UBERON:0000397	70.52	silver quality
lung	UBERON:0002048	70.22	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.93	silver quality
fallopian tube	UBERON:0003889	68.17	gold quality
sural nerve	UBERON:0015488	66.25	silver quality
pancreas	UBERON:0001264	65.41	gold quality
ganglionic eminence	UBERON:0004023	63.78	gold quality
prefrontal cortex	UBERON:0000451	63.71	gold quality
prostate gland	UBERON:0002367	62.66	gold quality
visceral pleura	UBERON:0002401	62.51	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	62.19	gold quality
caudate nucleus	UBERON:0001873	61.90	gold quality
hypothalamus	UBERON:0001898	61.63	gold quality
anterior cingulate cortex	UBERON:0009835	61.37	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	12.35

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.