CACNA1C-AS3

Summary

CACNA1C-AS3 (CACNA1C antisense RNA 3, HGNC:40117) is a long non-coding RNA gene on chromosome 12p13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40117
Approved symbol	CACNA1C-AS3
Name	CACNA1C antisense RNA 3
Location	12p13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256769
Ensembl biotype	lncRNA
Entrez	106478964
RNAcentral	URS000044232A — lncRNA, 444 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000543559

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000543559 — 2 exons

Exon	Start	End
ENSE00002212175	2603350	2603773
ENSE00002274216	2607421	2607440

Expression profiles

Bgee: expression breadth broad, 86 present calls, max score 70.20.

Top tissues by expression

86 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	70.20	gold quality
liver	UBERON:0002107	63.60	gold quality
bone marrow	UBERON:0002371	59.84	gold quality
islet of Langerhans	UBERON:0000006	58.56	gold quality
blood	UBERON:0000178	58.33	gold quality
monocyte	CL:0000576	56.88	gold quality
smooth muscle tissue	UBERON:0001135	56.66	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.48	gold quality
calcaneal tendon	UBERON:0003701	54.29	gold quality
urinary bladder	UBERON:0001255	54.27	silver quality
body of pancreas	UBERON:0001150	54.16	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.45	gold quality
prefrontal cortex	UBERON:0000451	53.22	gold quality
superior frontal gyrus	UBERON:0002661	51.26	gold quality
muscle of leg	UBERON:0001383	51.00	gold quality
myometrium	UBERON:0001296	49.31	gold quality
adrenal tissue	UBERON:0018303	48.90	gold quality
gastrocnemius	UBERON:0001388	48.84	gold quality
heart left ventricle	UBERON:0002084	48.65	gold quality
heart	UBERON:0000948	48.44	gold quality
popliteal artery	UBERON:0002250	47.98	gold quality
kidney	UBERON:0002113	47.92	silver quality
tibial artery	UBERON:0007610	47.89	gold quality
uterine cervix	UBERON:0000002	47.00	gold quality
ascending aorta	UBERON:0001496	46.99	gold quality
spleen	UBERON:0002106	46.67	gold quality
thoracic aorta	UBERON:0001515	46.43	gold quality
thoracic mammary gland	UBERON:0005200	46.20	silver quality
body of uterus	UBERON:0009853	45.89	gold quality
small intestine	UBERON:0002108	45.51	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.