CACNA1C-AS4

Summary

CACNA1C-AS4 (CACNA1C antisense RNA 4, HGNC:40116) is a long non-coding RNA gene on chromosome 12p13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40116
Approved symbol	CACNA1C-AS4
Name	CACNA1C antisense RNA 4
Location	12p13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256025
Ensembl biotype	lncRNA
Entrez	100874234
RNAcentral	URS000075B9D4 — lncRNA, 737 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000544415, ENST00000669813

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000544415 — 4 exons

Exon	Start	End
ENSE00002286563	2222200	2222420
ENSE00002305045	2220537	2220854
ENSE00002308670	2221615	2221695
ENSE00002315104	2223365	2223479

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 83.99.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0040 / max 3.5433, expressed in 2 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
128954	0.0040	2

Top tissues by expression

104 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.99	gold quality
colonic epithelium	UBERON:0000397	77.31	gold quality
bone marrow cell	CL:0002092	77.08	gold quality
urinary bladder	UBERON:0001255	68.35	gold quality
corpus callosum	UBERON:0002336	66.76	gold quality
uterine cervix	UBERON:0000002	65.94	gold quality
calcaneal tendon	UBERON:0003701	64.87	gold quality
kidney	UBERON:0002113	64.47	gold quality
sural nerve	UBERON:0015488	63.49	silver quality
tonsil	UBERON:0002372	62.50	silver quality
skeletal muscle tissue	UBERON:0001134	62.30	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.24	gold quality
lung	UBERON:0002048	58.85	gold quality
gall bladder	UBERON:0002110	57.38	gold quality
adult mammalian kidney	UBERON:0000082	57.30	gold quality
liver	UBERON:0002107	56.42	gold quality
left ovary	UBERON:0002119	56.17	gold quality
stomach	UBERON:0000945	55.28	gold quality
muscle of leg	UBERON:0001383	55.02	gold quality
adrenal gland	UBERON:0002369	54.70	gold quality
right testis	UBERON:0004534	54.09	gold quality
left testis	UBERON:0004533	54.05	gold quality
testis	UBERON:0000473	54.02	gold quality
primary visual cortex	UBERON:0002436	53.93	gold quality
small intestine	UBERON:0002108	53.80	gold quality
thoracic mammary gland	UBERON:0005200	53.70	silver quality
islet of Langerhans	UBERON:0000006	52.49	gold quality
adrenal tissue	UBERON:0018303	52.25	gold quality
monocyte	CL:0000576	52.15	silver quality
heart	UBERON:0000948	52.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.18

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.