CACNA1C-IT1

Summary

CACNA1C-IT1 (CACNA1C intronic transcript 1, HGNC:41312) is a long non-coding RNA gene on chromosome 12p13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41312
Approved symbol	CACNA1C-IT1
Name	CACNA1C intronic transcript 1
Location	12p13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256837
Ensembl biotype	lncRNA
Entrez	107984540
RNAcentral	URS00003F26A1 — lncRNA, 687 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000542984

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000542984 — 2 exons

Exon	Start	End
ENSE00002236471	2019926	2020532
ENSE00002321889	2018213	2018292

Expression profiles

Bgee: expression breadth broad, 64 present calls, max score 81.75.

Top tissues by expression

64 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.75	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.73	gold quality
urinary bladder	UBERON:0001255	65.27	gold quality
monocyte	CL:0000576	58.42	gold quality
islet of Langerhans	UBERON:0000006	56.30	gold quality
primary visual cortex	UBERON:0002436	52.60	gold quality
heart	UBERON:0000948	51.97	gold quality
prefrontal cortex	UBERON:0000451	51.96	gold quality
calcaneal tendon	UBERON:0003701	51.05	silver quality
right atrium auricular region	UBERON:0006631	51.03	gold quality
heart left ventricle	UBERON:0002084	50.11	gold quality
pancreas	UBERON:0001264	48.87	gold quality
right adrenal gland cortex	UBERON:0035827	47.24	gold quality
blood	UBERON:0000178	46.84	silver quality
endometrium	UBERON:0001295	46.25	gold quality
cerebellar cortex	UBERON:0002129	45.63	silver quality
caudate nucleus	UBERON:0001873	45.41	gold quality
gastrocnemius	UBERON:0001388	45.00	silver quality
tibial artery	UBERON:0007610	43.66	silver quality
body of pancreas	UBERON:0001150	43.59	silver quality
corpus callosum	UBERON:0002336	43.52	silver quality
Ammon’s horn	UBERON:0001954	43.28	silver quality
right adrenal gland	UBERON:0001233	42.72	gold quality
multicellular organism	UBERON:0000468	42.70	gold quality
left coronary artery	UBERON:0001626	42.62	silver quality
muscle layer of sigmoid colon	UBERON:0035805	42.54	gold quality
myometrium	UBERON:0001296	42.40	silver quality
nucleus accumbens	UBERON:0001882	42.30	silver quality
body of uterus	UBERON:0009853	42.21	silver quality
transverse colon	UBERON:0001157	41.93	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.