CACNA1C-IT3

Summary

CACNA1C-IT3 (CACNA1C intronic transcript 3, HGNC:41314) is a long non-coding RNA gene on chromosome 12p13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41314
Approved symbol	CACNA1C-IT3
Name	CACNA1C intronic transcript 3
Location	12p13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256721
Ensembl biotype	lncRNA
Entrez	100874370
RNAcentral	URS000075B8B9 — lncRNA, 430 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000542680, ENST00000783632, ENST00000783633

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000542680 — 3 exons

Exon	Start	End
ENSE00002203874	2288668	2288937
ENSE00002322500	2288019	2288204
ENSE00004157862	2269700	2269941

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 71.55.

Top tissues by expression

96 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	71.55	gold quality
left testis	UBERON:0004533	69.85	gold quality
urinary bladder	UBERON:0001255	69.45	gold quality
testis	UBERON:0000473	69.24	gold quality
right testis	UBERON:0004534	68.41	gold quality
tonsil	UBERON:0002372	62.48	silver quality
skeletal muscle tissue	UBERON:0001134	61.71	silver quality
corpus callosum	UBERON:0002336	58.95	gold quality
liver	UBERON:0002107	58.53	silver quality
calcaneal tendon	UBERON:0003701	55.86	gold quality
myometrium	UBERON:0001296	53.87	gold quality
lung	UBERON:0002048	53.51	gold quality
uterine cervix	UBERON:0000002	53.46	gold quality
stromal cell of endometrium	CL:0002255	53.38	silver quality
islet of Langerhans	UBERON:0000006	53.18	gold quality
small intestine	UBERON:0002108	52.38	gold quality
monocyte	CL:0000576	51.57	gold quality
prefrontal cortex	UBERON:0000451	51.33	gold quality
stomach	UBERON:0000945	51.25	gold quality
ovary	UBERON:0000992	51.06	gold quality
thoracic mammary gland	UBERON:0005200	50.38	silver quality
multicellular organism	UBERON:0000468	50.09	gold quality
kidney	UBERON:0002113	49.96	gold quality
cortex of kidney	UBERON:0001225	49.94	silver quality
adrenal tissue	UBERON:0018303	49.71	gold quality
heart left ventricle	UBERON:0002084	49.49	gold quality
heart	UBERON:0000948	49.42	gold quality
intestine	UBERON:0000160	48.69	gold quality
left ovary	UBERON:0002119	48.36	gold quality
endometrium	UBERON:0001295	47.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.