CACNA2D1-AS1

Summary

CACNA2D1-AS1 (CACNA2D1 antisense RNA 1, HGNC:40120) is a long non-coding RNA gene on chromosome 7q21.11.

Predicted to be involved in miRNA-mediated post-transcriptional gene silencing.

Source: NCBI Gene 101927356 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40120
Approved symbol	CACNA2D1-AS1
Name	CACNA2D1 antisense RNA 1
Location	7q21.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223770
Ensembl biotype	lncRNA
Entrez	101927356
RNAcentral	URS000037910D — lncRNA, 2651 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000439234, ENST00000454066

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439234 — 5 exons

Exon	Start	End
ENSE00001636925	82023843	82023897
ENSE00001652493	82021122	82021205
ENSE00001756044	82020810	82020934
ENSE00001792865	82027655	82029955
ENSE00001801469	82009177	82009262

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 77.86.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.86	silver quality
corpus callosum	UBERON:0002336	77.17	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.64	gold quality
skeletal muscle tissue	UBERON:0001134	69.64	gold quality
adrenal tissue	UBERON:0018303	67.51	gold quality
colonic epithelium	UBERON:0000397	67.34	silver quality
hindlimb stylopod muscle	UBERON:0004252	65.21	gold quality
sural nerve	UBERON:0015488	64.82	silver quality
calcaneal tendon	UBERON:0003701	64.66	gold quality
cortical plate	UBERON:0005343	62.21	gold quality
ganglionic eminence	UBERON:0004023	61.31	gold quality
monocyte	CL:0000576	54.91	gold quality
islet of Langerhans	UBERON:0000006	54.65	gold quality
stromal cell of endometrium	CL:0002255	54.32	silver quality
blood	UBERON:0000178	53.97	gold quality
muscle of leg	UBERON:0001383	53.25	gold quality
liver	UBERON:0002107	53.22	gold quality
bone marrow	UBERON:0002371	52.79	silver quality
gastrocnemius	UBERON:0001388	52.50	gold quality
lymph node	UBERON:0000029	52.15	gold quality
duodenum	UBERON:0002114	52.13	gold quality
pancreas	UBERON:0001264	52.12	gold quality
lower esophagus mucosa	UBERON:0035834	51.91	gold quality
prefrontal cortex	UBERON:0000451	51.87	gold quality
endometrium	UBERON:0001295	51.54	silver quality
tonsil	UBERON:0002372	51.03	gold quality
superior frontal gyrus	UBERON:0002661	50.86	gold quality
urinary bladder	UBERON:0001255	50.65	gold quality
body of pancreas	UBERON:0001150	50.06	gold quality
kidney	UBERON:0002113	49.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.