CACNA2D3-AS1

Summary

CACNA2D3-AS1 (CACNA2D3 antisense RNA 1, HGNC:40702) is a long non-coding RNA gene on chromosome 3p14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40702
Approved symbol	CACNA2D3-AS1
Name	CACNA2D3 antisense RNA 1
Location	3p14.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000243715
Ensembl biotype	lncRNA
Entrez	100874237
RNAcentral	URS0000479C59 — lncRNA, 2078 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000471265, ENST00000768747

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000471265 — 7 exons

Exon	Start	End
ENSE00001836925	54874605	54875710
ENSE00001843093	54901159	54901255
ENSE00001865974	54876269	54876311
ENSE00001911091	54894613	54894755
ENSE00001924247	54878688	54878944
ENSE00001933409	54877016	54877154
ENSE00001939757	54896666	54896958

Expression profiles

Bgee: expression breadth broad, 81 present calls, max score 67.40.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0157 / max 4.1427, expressed in 10 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
42530	0.0157	10

Top tissues by expression

81 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	67.40	silver quality
uterine cervix	UBERON:0000002	58.67	gold quality
ectocervix	UBERON:0012249	57.50	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.18	silver quality
calcaneal tendon	UBERON:0003701	52.89	silver quality
corpus callosum	UBERON:0002336	52.51	gold quality
right ovary	UBERON:0002118	52.13	gold quality
cerebellar hemisphere	UBERON:0002245	51.55	gold quality
right atrium auricular region	UBERON:0006631	50.99	gold quality
lymph node	UBERON:0000029	50.38	silver quality
vagina	UBERON:0000996	50.17	gold quality
prefrontal cortex	UBERON:0000451	49.26	gold quality
lower esophagus mucosa	UBERON:0035834	49.15	gold quality
ovary	UBERON:0000992	48.80	gold quality
placenta	UBERON:0001987	48.71	gold quality
heart	UBERON:0000948	48.56	gold quality
apex of heart	UBERON:0002098	48.47	gold quality
esophagus mucosa	UBERON:0002469	48.18	gold quality
left ovary	UBERON:0002119	48.02	gold quality
right lung	UBERON:0002167	47.98	gold quality
primary visual cortex	UBERON:0002436	47.84	gold quality
adrenal gland	UBERON:0002369	47.60	silver quality
muscle of leg	UBERON:0001383	47.51	silver quality
endocervix	UBERON:0000458	47.14	gold quality
superior frontal gyrus	UBERON:0002661	46.96	silver quality
left coronary artery	UBERON:0001626	46.89	gold quality
gastrocnemius	UBERON:0001388	46.74	silver quality
heart left ventricle	UBERON:0002084	46.42	gold quality
kidney	UBERON:0002113	46.32	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	45.89	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.