CADM3-AS1

Summary

CADM3-AS1 (CADM3 antisense RNA 1, HGNC:40812) is a long non-coding RNA gene on chromosome 1q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40812
Approved symbol	CADM3-AS1
Name	CADM3 antisense RNA 1
Location	1q23.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	CTA-134P22.2
Ensembl gene	ENSG00000225670
Ensembl biotype	lncRNA
Entrez	100131825
RNAcentral	URS0000759D0A — lncRNA, 3294 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000415675, ENST00000609696, ENST00000815412, ENST00000815413, ENST00000815414, ENST00000815415, ENST00000815416, ENST00000847525

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415675 — 4 exons

Exon	Start	End
ENSE00001643960	159194325	159198221
ENSE00001654506	159199786	159199859
ENSE00001686398	159202250	159202512
ENSE00001730110	159200812	159201621

Expression profiles

Bgee: expression breadth ubiquitous, 162 present calls, max score 82.82.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0547 / max 10.0113, expressed in 28 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
15370	0.0273	16
15369	0.0171	4
15368	0.0103	3

Top tissues by expression

284 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right hemisphere of cerebellum	UBERON:0014890	82.82	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.58	gold quality
prefrontal cortex	UBERON:0000451	81.87	gold quality
cerebellar hemisphere	UBERON:0002245	81.62	gold quality
cerebellar cortex	UBERON:0002129	81.39	gold quality
mucosa of stomach	UBERON:0001199	80.45	gold quality
spleen	UBERON:0002106	79.95	gold quality
left uterine tube	UBERON:0001303	79.62	gold quality
cerebellum	UBERON:0002037	77.99	gold quality
tibial nerve	UBERON:0001323	76.51	gold quality
tendon of biceps brachii	UBERON:0008188	74.82	gold quality
lower esophagus muscularis layer	UBERON:0035833	74.43	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	74.37	gold quality
lower esophagus	UBERON:0013473	74.34	gold quality
ectocervix	UBERON:0012249	73.74	gold quality
endocervix	UBERON:0000458	72.37	gold quality
ganglionic eminence	UBERON:0004023	72.30	gold quality
ventricular zone	UBERON:0003053	72.13	gold quality
cortical plate	UBERON:0005343	71.93	gold quality
omental fat pad	UBERON:0010414	71.82	gold quality
peritoneum	UBERON:0002358	71.74	gold quality
apex of heart	UBERON:0002098	71.38	gold quality
subcutaneous adipose tissue	UBERON:0002190	71.35	gold quality
body of uterus	UBERON:0009853	70.85	gold quality
left coronary artery	UBERON:0001626	70.43	gold quality
esophagus	UBERON:0001043	70.40	gold quality
smooth muscle tissue	UBERON:0001135	70.17	gold quality
adipose tissue of abdominal region	UBERON:0007808	70.15	gold quality
diaphragm	UBERON:0001103	69.69	gold quality
right coronary artery	UBERON:0001625	69.01	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.05

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.