CALCRL-AS1

Summary

CALCRL-AS1 (CALCRL and TFPI antisense RNA 1, HGNC:55863) is a long non-coding RNA gene on chromosome 2q32.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55863
Approved symbol	CALCRL-AS1
Name	CALCRL and TFPI antisense RNA 1
Location	2q32.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224063
Ensembl biotype	lncRNA
Entrez	105373786
RNAcentral	URS00026A2825 — lncRNA, 2327 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000412276, ENST00000428329, ENST00000453517, ENST00000729958, ENST00000729959, ENST00000729960, ENST00000759350, ENST00000759351, ENST00000759352, ENST00000759353, ENST00000759354

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412276 — 8 exons

Exon	Start	End
ENSE00001646643	187003274	187003365
ENSE00001683434	187546729	187546839
ENSE00001688668	187554276	187554393
ENSE00001717024	187191835	187191931
ENSE00001726510	187547078	187547163
ENSE00001753554	187547483	187547707
ENSE00001759862	187499506	187499605
ENSE00003867746	187555935	187556288

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 85.73.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.73	gold quality
liver	UBERON:0002107	82.74	gold quality
right lobe of liver	UBERON:0001114	82.49	gold quality
lower esophagus mucosa	UBERON:0035834	79.46	gold quality
sural nerve	UBERON:0015488	78.52	gold quality
calcaneal tendon	UBERON:0003701	77.00	gold quality
adrenal tissue	UBERON:0018303	74.84	gold quality
lung	UBERON:0002048	71.93	gold quality
right lung	UBERON:0002167	71.63	gold quality
esophagus mucosa	UBERON:0002469	71.55	gold quality
tonsil	UBERON:0002372	71.31	gold quality
gall bladder	UBERON:0002110	71.13	gold quality
upper lobe of left lung	UBERON:0008952	69.81	gold quality
islet of Langerhans	UBERON:0000006	69.74	gold quality
placenta	UBERON:0001987	69.50	gold quality
bone marrow cell	CL:0002092	69.43	silver quality
right atrium auricular region	UBERON:0006631	69.38	gold quality
ganglionic eminence	UBERON:0004023	68.49	gold quality
skeletal muscle tissue	UBERON:0001134	67.84	gold quality
esophagus	UBERON:0001043	67.44	gold quality
right adrenal gland cortex	UBERON:0035827	67.43	gold quality
right adrenal gland	UBERON:0001233	66.77	gold quality
skin of abdomen	UBERON:0001416	66.74	gold quality
zone of skin	UBERON:0000014	66.31	gold quality
ascending aorta	UBERON:0001496	66.20	gold quality
adrenal gland	UBERON:0002369	66.08	gold quality
thyroid gland	UBERON:0002046	66.01	gold quality
muscle tissue	UBERON:0002385	65.99	gold quality
heart	UBERON:0000948	65.91	gold quality
left lobe of thyroid gland	UBERON:0001120	65.89	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	9.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.