CAMKV

Summary

CAMKV (CaM kinase like vesicle associated, HGNC:28788) is a protein-coding gene on chromosome 3p21.31, encoding CaM kinase-like vesicle-associated protein (Q8NCB2). Does not appear to have detectable kinase activity.

Predicted to enable calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Predicted to be active in cytoplasm; glutamatergic synapse; and postsynapse.

Source: NCBI Gene 79012 — RefSeq curated summary.

At a glance

• GWAS associations: 22
• Clinical variants (ClinVar): 34 total
• MANE Select transcript: NM_024046

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:28788
Approved symbol	CAMKV
Name	CaM kinase like vesicle associated
Location	3p21.31
Locus type	gene with protein product
Status	Approved
Aliases	MGC8407, VACAMKL
Ensembl gene	ENSG00000164076
Ensembl biotype	protein_coding
OMIM	614993
Entrez	79012

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 13 protein_coding, 6 retained_intron, 2 nonsense_mediated_decay, 1 protein_coding_CDS_not_defined

ENST00000296471, ENST00000463537, ENST00000466535, ENST00000466940, ENST00000467248, ENST00000472895, ENST00000475665, ENST00000476105, ENST00000477224, ENST00000478149, ENST00000479704, ENST00000480398, ENST00000483811, ENST00000487726, ENST00000488336, ENST00000498324, ENST00000620470, ENST00000865409, ENST00000911456, ENST00000911457, ENST00000951010, ENST00000951011

RefSeq mRNA: 2 — MANE Select: NM_024046 NM_001320147, NM_024046

CCDS: CCDS33762, CCDS82776

Canonical transcript exons

ENST00000477224 — 11 exons

Exon	Start	End
ENSE00001278153	49857989	49859881
ENSE00002025285	49869758	49869906
ENSE00003462570	49862294	49862402
ENSE00003475157	49861791	49861865
ENSE00003504579	49860943	49861018
ENSE00003531850	49861439	49861577
ENSE00003537236	49860471	49860549
ENSE00003581903	49861180	49861300
ENSE00003623695	49862045	49862176
ENSE00003669474	49860716	49860852
ENSE00003693033	49860171	49860258

Expression profiles

Bgee: expression breadth ubiquitous, 141 present calls, max score 99.39.

FANTOM5 (CAGE): breadth broad, TPM avg 12.4536 / max 792.2294, expressed in 335 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
42283	12.4536	335

Top tissues by expression

263 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	99.39	gold quality
nucleus accumbens	UBERON:0001882	97.51	gold quality
prefrontal cortex	UBERON:0000451	96.89	gold quality
right frontal lobe	UBERON:0002810	96.38	gold quality
caudate nucleus	UBERON:0001873	96.30	gold quality
putamen	UBERON:0001874	95.92	gold quality
anterior cingulate cortex	UBERON:0009835	95.79	gold quality
cingulate cortex	UBERON:0003027	95.76	gold quality
Brodmann (1909) area 9	UBERON:0013540	95.62	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	95.51	gold quality
frontal cortex	UBERON:0001870	95.23	gold quality
neocortex	UBERON:0001950	94.82	gold quality
cerebral cortex	UBERON:0000956	93.95	gold quality
telencephalon	UBERON:0001893	93.69	gold quality
amygdala	UBERON:0001876	93.58	gold quality
ganglionic eminence	UBERON:0004023	93.36	gold quality
Ammon’s horn	UBERON:0001954	92.49	gold quality
forebrain	UBERON:0001890	92.08	gold quality
orbitofrontal cortex	UBERON:0004167	91.88	gold quality
temporal lobe	UBERON:0001871	91.53	gold quality
Brodmann (1909) area 46	UBERON:0006483	91.20	gold quality
superior frontal gyrus	UBERON:0002661	90.38	gold quality
hypothalamus	UBERON:0001898	90.01	gold quality
CA1 field of hippocampus	UBERON:0003881	89.49	gold quality
entorhinal cortex	UBERON:0002728	89.19	gold quality
middle temporal gyrus	UBERON:0002771	88.21	gold quality
brain	UBERON:0000955	88.15	gold quality
postcentral gyrus	UBERON:0002581	88.08	gold quality
primary visual cortex	UBERON:0002436	87.05	gold quality
parietal lobe	UBERON:0001872	86.82	gold quality

Single-cell (SCXA)

Detected in 3 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-HCAD-5	yes	63.23
E-GEOD-93593	yes	7.10
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

96 targeting CAMKV, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-4476	100.00	68.18	2030
HSA-MIR-6876-5P	100.00	67.68	2126
HSA-MIR-8485	100.00	77.57	4731
HSA-MIR-4747-5P	100.00	67.90	2681
HSA-MIR-5196-5P	100.00	67.98	2761
HSA-MIR-4776-3P	100.00	68.73	1340
HSA-MIR-4533	100.00	69.48	2758
HSA-MIR-6870-5P	99.99	68.55	2115
HSA-MIR-4723-5P	99.97	68.70	2034
HSA-MIR-5698	99.97	68.49	2029
HSA-MIR-7111-5P	99.97	68.48	2062
HSA-MIR-6768-5P	99.92	67.36	1942
HSA-MIR-329-3P	99.91	66.56	1234
HSA-MIR-362-3P	99.91	66.38	1267
HSA-MIR-548E-5P	99.89	72.73	4486
HSA-MIR-4492	99.87	68.25	3611
HSA-MIR-3941	99.86	70.54	2735
HSA-MIR-4447	99.85	67.81	2900
HSA-MIR-544A	99.84	68.66	1965
HSA-MIR-548AJ-5P	99.78	71.12	3085
HSA-MIR-548F-5P	99.78	71.02	3093
HSA-MIR-548G-5P	99.78	71.12	3085
HSA-MIR-548X-5P	99.78	71.12	3085
HSA-MIR-6752-3P	99.72	66.71	1587
HSA-MIR-4755-5P	99.71	70.34	2716
HSA-MIR-5006-3P	99.71	70.26	2728
HSA-MIR-6762-3P	99.66	66.94	1188
HSA-MIR-10394-5P	99.65	66.83	1852
HSA-MIR-1205	99.65	66.76	1826
HSA-MIR-6132	99.60	65.83	1554

Cross-species orthologs

4 orthologs

Organism	Symbol	Gene ID
danio_rerio	camkvb	ENSDARG00000005141
danio_rerio	camkva	ENSDARG00000027963
mus_musculus	Camkv	ENSMUSG00000032936
rattus_norvegicus	Camkv	ENSRNOG00000058938

Paralogs (22): CAMKK1 (ENSG00000004660), CAMK1G (ENSG00000008118), CAMK2B (ENSG00000058404), CAMK2A (ENSG00000070808), MYLK2 (ENSG00000101306), CAMKK2 (ENSG00000110931), STK11 (ENSG00000118046), STK33 (ENSG00000130413), PNCK (ENSG00000130822), DCLK1 (ENSG00000133083), CAMK1 (ENSG00000134072), MYLK3 (ENSG00000140795), CAMK2D (ENSG00000145349), MYLK4 (ENSG00000145949), PSKH2 (ENSG00000147613), CAMK2G (ENSG00000148660), PHKG2 (ENSG00000156873), PSKH1 (ENSG00000159792), DCLK3 (ENSG00000163673), PHKG1 (ENSG00000164776), DCLK2 (ENSG00000170390), CAMK1D (ENSG00000183049)

Protein

Protein identifiers

CaM kinase-like vesicle-associated protein — Q8NCB2 (reviewed: Q8NCB2)

All UniProt accessions (8): A0A140VKD5, B4DM24, B4DSW8, C9J9E2, C9JSB2, E7ETR1, Q8NCB2, F8WDJ4

UniProt curated annotations — full annotation on UniProt →

Function. Does not appear to have detectable kinase activity.

Subunit / interactions. Interacts with calmodulin, in the presence of calcium.

Subcellular location. Cell membrane. Cytoplasmic vesicle membrane.

Domain organisation. The protein kinase domain is predicted to be catalytically inactive.

Similarity. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

Isoforms (3)

UniProt ID	Names	Canonical?
Q8NCB2-1	1	yes
Q8NCB2-2	2
Q8NCB2-3	3

RefSeq proteins (2): NP_001307076, NP_076951* (*=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR000719	Prot_kinase_dom	Domain
IPR011009	Kinase-like_dom_sf	Homologous_superfamily

Pfam: PF00069

UniProt features (19 total): sequence variant 6, sequence conflict 3, compositionally biased region 3, modified residue 2, splice variant 2, chain 1, domain 1, region of interest 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q8NCB2-F1	72.88	0.48

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (2): 435, 459

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 134 (showing top): TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497, LFA1_Q6, GCANCTGNY_MYOD_Q6, USF_C, CAGCTG_AP4_Q5, EFC_Q6, GOBP_CELL_CELL_SIGNALING, GOBP_CELL_JUNCTION_ORGANIZATION, MYCMAX_01, HEN1_01, GRE_C, SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN, OCT1_07, GOBP_SYNAPTIC_SIGNALING, GOBP_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY

GO Biological Process (4): signal transduction (GO:0007165), modulation of chemical synaptic transmission (GO:0050804), regulation of modification of postsynaptic structure (GO:0099159), protein phosphorylation (GO:0006468)

GO Molecular Function (5): calcium/calmodulin-dependent protein kinase activity (GO:0004683), calmodulin binding (GO:0005516), ATP binding (GO:0005524), protein kinase activity (GO:0004672), kinase activity (GO:0016301)

GO Cellular Component (7): cytoplasm (GO:0005737), plasma membrane (GO:0005886), cytoplasmic vesicle membrane (GO:0030659), synapse (GO:0045202), glutamatergic synapse (GO:0098978), membrane (GO:0016020), cytoplasmic vesicle (GO:0031410)

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
cellular anatomical structure	2
cell communication	1
cellular process	1
signaling	1
regulation of cellular process	1
cellular response to stimulus	1
chemical synaptic transmission	1
regulation of trans-synaptic signaling	1
modification of postsynaptic structure	1
regulation of modification of synaptic structure	1
phosphorylation	1
protein modification process	1
protein serine/threonine kinase activity	1
protein binding	1
adenyl ribonucleotide binding	1
purine ribonucleoside triphosphate binding	1
kinase activity	1
phosphotransferase activity, alcohol group as acceptor	1
catalytic activity, acting on a protein	1
transferase activity, transferring phosphorus-containing groups	1
intracellular anatomical structure	1
membrane	1
cell periphery	1
vesicle membrane	1
cytoplasmic vesicle	1
cell junction	1
synapse	1
cytoplasm	1
intracellular vesicle	1

Protein interactions and networks

STRING

2273 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
CAMKV	GRIK4	Q16099	451
CAMKV	SYT1	P21579	449
CAMKV	NCDN	Q9UBB6	438
CAMKV	KANSL1	Q7Z3B3	434
CAMKV	SLC1A3	P43003	429
CAMKV	LSAMP	Q13449	427
CAMKV	CDHR4	A6H8M9	419
CAMKV	GAP43	P17677	418
CAMKV	GORASP2	Q9H8Y8	414
CAMKV	PPP3CC	P48454	401
CAMKV	NDUFS4	O43181	395
CAMKV	RAP2A	P10114	394
CAMKV	GSTK1	Q9Y2Q3	383
CAMKV	PRR14	Q9BWN1	377
CAMKV	TEPSIN	Q96N21	367

IntAct

42 interactions, top by confidence:

A	B	Type	Score
CAMKV	AP3B1	psi-mi:“MI:0914”(association)	0.640
SDC2	PDPK1	psi-mi:“MI:0914”(association)	0.640
TMEM182	LGALS3	psi-mi:“MI:0914”(association)	0.560
NUFIP1	PDE2A	psi-mi:“MI:0914”(association)	0.530
PRICKLE3	SIAH2	psi-mi:“MI:0914”(association)	0.530
RIT1	MAD2L1BP	psi-mi:“MI:0914”(association)	0.530
PRICKLE3	METTL18	psi-mi:“MI:0914”(association)	0.530
FAM114A2	CAMKV	psi-mi:“MI:0915”(physical association)	0.400
HSP90AB1	CAMKV	psi-mi:“MI:0915”(physical association)	0.400
CAMKV	CFTR	psi-mi:“MI:0915”(physical association)	0.370
CFTR	CAMKV	psi-mi:“MI:0915”(physical association)	0.370
COPS5	FBLL1	psi-mi:“MI:0914”(association)	0.350
MAPT	SHTN1	psi-mi:“MI:0914”(association)	0.350
SCN2A	IGLL5	psi-mi:“MI:0914”(association)	0.350
CACNA1C	SYT5	psi-mi:“MI:0914”(association)	0.350
CACNA1C	IGLL5	psi-mi:“MI:0914”(association)	0.350
CACNA1C	CACNB4	psi-mi:“MI:0914”(association)	0.350
RIMS1	PSMD12	psi-mi:“MI:0914”(association)	0.350
CACNA1C	DISP2	psi-mi:“MI:0914”(association)	0.350
SYT2	ARHGAP10	psi-mi:“MI:0914”(association)	0.350
RNPS1	C1orf226	psi-mi:“MI:0914”(association)	0.350
CD6	CIBAR1	psi-mi:“MI:0914”(association)	0.350
CD44	TCAF2	psi-mi:“MI:0914”(association)	0.350
GPM6A	KIF2A	psi-mi:“MI:0914”(association)	0.350
HAX1	DNM1L	psi-mi:“MI:0914”(association)	0.350

BioGRID (188): CAMKV (Affinity Capture-MS), CAMKV (Affinity Capture-MS), CAMKV (Affinity Capture-MS), CAMKV (Affinity Capture-MS), CAMKV (Affinity Capture-MS), UBTF (Affinity Capture-MS), GPC1 (Affinity Capture-MS), BRD2 (Affinity Capture-MS), AFF4 (Affinity Capture-MS), AFF1 (Affinity Capture-MS), MLLT3 (Affinity Capture-MS), NRXN3 (Affinity Capture-MS), AHCYL2 (Affinity Capture-MS), CWC22 (Affinity Capture-MS), ACIN1 (Affinity Capture-MS)

ESM2 similar proteins: A3KFM7, A4IFM7, D3ZA12, O48963, O75914, O77708, O88643, P07313, P08413, P08414, P11730, P11799, P13234, P15791, P27466, P29294, P35465, P70402, Q05623, Q08E52, Q13153, Q13177, Q13554, Q13555, Q16566, Q17850, Q28824, Q29502, Q38870, Q3B8Q1, Q3MHJ9, Q3UHL1, Q61036, Q62829, Q63092, Q64303, Q6DGS3, Q6P3Q4, Q6PA14, Q7SY49

Diamond homologs: A8WXF6, A8X6H4, B3NKK1, B4GXC2, B4IMC3, B4IT27, B4NSS9, B5DK35, D2I3C6, O08875, O14408, O15075, O15865, O42844, O49717, O62305, O70150, O77708, P08413, P08414, P11275, P11730, P11798, P11801, P13234, P15791, P25323, P27466, P28582, P28583, P28652, P34101, P93759, Q00168, Q00771, Q0V7M1, Q13554, Q13555, Q13557, Q14012

SIGNOR signaling

0 interactions.

Enriched among interaction partners

Reactome pathways and GO biological processes over-represented among this gene’s 59 IntAct physical interaction partners (hypergeometric vs the genome-wide background, BH-FDR, gene-set size 15–500, ranked by fold). A functional readout of the neighbourhood — distinct from this gene’s own memberships above, and biased toward well-studied / hub proteins, so read it as themes rather than proof.

Reactome pathways:

Pathway	Partners	Fold	FDR
Axon guidance	7	8.3×	4e-03
Nervous system development	7	7.9×	4e-03

Disease & clinical

Clinical variants and AI predictions

ClinVar

34 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	28
Likely benign	3
Benign	3

Top pathogenic / likely-pathogenic (0)

SpliceAI

1828 predictions. Top by Δscore:

Variant	Effect	Δscore
3:49859877:GCCTT:G	acceptor_gain	1.0000
3:49859878:CCTT:C	acceptor_loss	1.0000
3:49859878:CCTTC:C	acceptor_gain	1.0000
3:49859879:CTT:C	acceptor_gain	1.0000
3:49859880:TT:T	acceptor_gain	1.0000
3:49859880:TTCT:T	acceptor_loss	1.0000
3:49859881:TCTGA:T	acceptor_loss	1.0000
3:49859882:C:CC	acceptor_gain	1.0000
3:49859882:C:G	acceptor_loss	1.0000
3:49859883:T:A	acceptor_loss	1.0000
3:49859892:CACAG:C	acceptor_gain	1.0000
3:49859894:CAG:C	acceptor_gain	1.0000
3:49859895:A:T	acceptor_gain	1.0000
3:49860165:CCTTA:C	donor_loss	1.0000
3:49860166:CTTAC:C	donor_loss	1.0000
3:49860167:TTAC:T	donor_loss	1.0000
3:49860168:TA:T	donor_loss	1.0000
3:49860169:A:C	donor_loss	1.0000
3:49860259:C:A	acceptor_loss	1.0000
3:49860467:TCACC:T	donor_loss	1.0000
3:49860468:CACCA:C	donor_loss	1.0000
3:49860469:A:AC	donor_gain	1.0000
3:49860469:A:C	donor_loss	1.0000
3:49860469:AC:A	donor_gain	1.0000
3:49860470:C:CC	donor_gain	1.0000
3:49860470:CC:C	donor_gain	1.0000
3:49860470:CCA:C	donor_gain	1.0000
3:49860470:CCACT:C	donor_gain	1.0000
3:49860545:TTTGG:T	acceptor_gain	1.0000
3:49860546:TTGG:T	acceptor_gain	1.0000

AlphaMissense

3269 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
3:49859874:A:T	V317D	1.000
3:49859877:G:T	A316D	1.000
3:49859878:C:G	A316P	1.000
3:49860174:C:A	W313C	1.000
3:49860174:C:G	W313C	1.000
3:49860175:C:G	W313S	1.000
3:49860176:A:G	W313R	1.000
3:49860176:A:T	W313R	1.000
3:49860258:C:A	W285C	1.000
3:49860258:C:G	W285C	1.000
3:49860472:A:G	W285R	1.000
3:49860472:A:T	W285R	1.000
3:49860487:C:G	A280P	1.000
3:49860528:A:G	L266P	1.000
3:49860537:A:T	V263D	1.000
3:49860540:A:G	L262P	1.000
3:49860545:T:A	K260N	1.000
3:49860545:T:G	K260N	1.000
3:49860549:G:T	A259D	1.000
3:49860724:G:C	S256W	1.000
3:49860735:C:A	W252C	1.000
3:49860735:C:G	W252C	1.000
3:49860736:C:G	W252S	1.000
3:49860737:A:G	W252R	1.000
3:49860737:A:T	W252R	1.000
3:49860772:A:C	I240S	1.000
3:49860780:G:C	F237L	1.000
3:49860780:G:T	F237L	1.000
3:49860782:A:G	F237L	1.000
3:49860831:G:C	F220L	1.000

dbSNP variants (sampled 300 via entrez): RS1000752391 (3:49870295 TGGGCAGTC>T), RS1000921712 (3:49863152 C>T), RS1001093669 (3:49857716 A>G), RS1001246464 (3:49871640 G>C), RS1001616323 (3:49868935 G>C), RS1001798379 (3:49863975 A>G), RS1002232592 (3:49869386 G>A,C), RS1002266293 (3:49858819 C>G), RS1002498837 (3:49859541 G>A), RS1002525235 (3:49862989 G>A), RS1002619226 (3:49870747 T>A,C), RS1003005846 (3:49870448 G>A), RS1003240734 (3:49867692 G>A), RS1003269910 (3:49868094 A>C), RS1003341242 (3:49868676 T>A,C)

Disease associations

OMIM: gene MIM:614993 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

22 associations (top):

Study	Trait	p-value
GCST003496_9	Educational attainment	4.000000e-14
GCST003795_3	Age at first birth	5.000000e-15
GCST004280_89	Diastolic blood pressure	5.000000e-09
GCST005316_115	Intelligence (MTAG)	6.000000e-12
GCST005316_119	Intelligence (MTAG)	6.000000e-29
GCST006044_2	Age at first birth	2.000000e-06
GCST006045_5	Age at first birth	6.000000e-10
GCST006269_685	General cognitive ability	8.000000e-10
GCST006920_7	Regular attendance at a gym or sports club	6.000000e-10
GCST006922_9	Regular attendance at a religious group	3.000000e-08
GCST007044_11	Extremely high intelligence	4.000000e-08
GCST007559_24	Sleep duration (short sleep)	3.000000e-08
GCST007565_87	Morning person	3.000000e-18
GCST009524_140	Household income (MTAG)	1.000000e-31
GCST010002_422	Refractive error	4.000000e-14
GCST010698_80	Subcortical volume (min-P)	3.000000e-24
GCST010699_110	Brain morphology (min-P)	4.000000e-08
GCST010701_52	Cortical surface area (MOSTest)	1.000000e-16
GCST010702_36	Subcortical volume (MOSTest)	1.000000e-10
GCST010703_262	Brain morphology (MOSTest)	2.000000e-13
GCST012332_55	Multisite chronic pain	5.000000e-09
GCST90000050_22	Age at first birth	6.000000e-33

EFO canonical traits (9, from GWAS)

EFO ID	Trait name
EFO:0004784	self reported educational attainment
EFO:0009101	age at first birth measurement
EFO:0006336	diastolic blood pressure
EFO:0004337	intelligence
EFO:0009592	social interaction measurement
EFO:0008328	chronotype measurement
EFO:0009695	household income
EFO:0004346	neuroimaging measurement
EFO:0010100	multisite chronic pain

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

GtoPdb / IUPHAR curated pharmacology

(IUPHAR/BPS Guide to Pharmacology — expert-curated)

Target class: enzyme — CAMK-unique family

CTD chemical–gene interactions

26 total (human), top 26 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Phenylmercuric Acetate	affects cotreatment, decreases expression	2
ethylbenzene	affects cotreatment, decreases expression	1
propionaldehyde	increases expression	1
beta-lapachone	increases expression	1
sodium arsenite	decreases expression	1
butyraldehyde	increases expression	1
benzo(e)pyrene	increases methylation	1
pentanal	increases expression	1
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	affects cotreatment, decreases expression	1
dorsomorphin	affects cotreatment, decreases expression	1
Aldehydes	increases expression	1
Benzo(a)pyrene	affects methylation, increases methylation	1
Cadmium	decreases expression, increases abundance	1
Carbamazepine	affects expression	1
Diethylhexyl Phthalate	decreases expression	1
Diethylnitrosamine	increases expression	1
Estradiol	increases expression	1
Ivermectin	decreases expression	1
Methapyrilene	increases methylation	1
Tobacco Smoke Pollution	increases expression	1
Toluene	affects cotreatment, decreases expression	1
Tretinoin	decreases expression	1
Valproic Acid	increases methylation	1
Xylenes	affects cotreatment, decreases expression	1
Aflatoxin B1	increases methylation	1
Cadmium Chloride	decreases expression, increases abundance	1

Cellosaurus cell lines

3 cell lines: 3 cancer cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_SG72	HAP1 CAMKV (-) 1	Cancer cell line	Male
CVCL_SG73	HAP1 CAMKV (-) 2	Cancer cell line	Male
CVCL_SG74	HAP1 CAMKV (-) 3	Cancer cell line	Male

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.