CAPS2-AS1

Summary

CAPS2-AS1 (CAPS2 antisense RNA 1, HGNC:40769) is a long non-coding RNA gene on chromosome 12q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40769
Approved symbol	CAPS2-AS1
Name	CAPS2 antisense RNA 1
Location	12q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254451
Ensembl biotype	lncRNA
Entrez	107983975
RNAcentral	URS0002A5BB5A — lncRNA, 1791 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000534648, ENST00000548779, ENST00000549953, ENST00000751474

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000534648 — 2 exons

Exon	Start	End
ENSE00002190694	75295056	75295168
ENSE00002201177	75298200	75298508

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 90.10.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0102 / max 7.7308, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
126896	0.0102	3

Top tissues by expression

217 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.10	gold quality
left testis	UBERON:0004533	78.45	gold quality
right testis	UBERON:0004534	77.31	gold quality
testis	UBERON:0000473	75.17	gold quality
right uterine tube	UBERON:0001302	66.27	gold quality
monocyte	CL:0000576	63.35	gold quality
smooth muscle tissue	UBERON:0001135	61.31	gold quality
stromal cell of endometrium	CL:0002255	58.32	gold quality
gall bladder	UBERON:0002110	57.59	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.47	gold quality
calcaneal tendon	UBERON:0003701	56.14	gold quality
sural nerve	UBERON:0015488	55.07	silver quality
muscle of leg	UBERON:0001383	54.94	gold quality
gastrocnemius	UBERON:0001388	54.64	gold quality
prefrontal cortex	UBERON:0000451	53.84	gold quality
heart left ventricle	UBERON:0002084	52.03	gold quality
right adrenal gland cortex	UBERON:0035827	51.86	gold quality
right adrenal gland	UBERON:0001233	51.79	gold quality
cardiac ventricle	UBERON:0002082	51.40	gold quality
islet of Langerhans	UBERON:0000006	51.11	gold quality
descending thoracic aorta	UBERON:0002345	50.89	gold quality
cortex of kidney	UBERON:0001225	50.40	gold quality
heart	UBERON:0000948	50.20	gold quality
body of pancreas	UBERON:0001150	50.16	gold quality
metanephros cortex	UBERON:0010533	49.66	gold quality
left adrenal gland cortex	UBERON:0035825	49.59	gold quality
adrenal cortex	UBERON:0001235	49.28	gold quality
pancreas	UBERON:0001264	49.09	gold quality
left adrenal gland	UBERON:0001234	48.87	gold quality
adrenal gland	UBERON:0002369	48.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.