CARD11-AS1
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Summary
CARD11-AS1 (CARD11 antisense RNA 1, HGNC:40766) is a long non-coding RNA gene on chromosome 7p22.2.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:40766 |
| Approved symbol | CARD11-AS1 |
| Name | CARD11 antisense RNA 1 |
| Location | 7p22.2 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000237286 |
| Ensembl biotype | lncRNA |
| Entrez | 101927256 |
| RNAcentral | URS00026A2831 — lncRNA, 965 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 2 — 2 lncRNA
ENST00000423194, ENST00000816600
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000423194 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001735297 | 2944035 | 2944508 |
| ENSE00001795163 | 2946597 | 2947091 |
Expression profiles
Bgee: expression breadth broad, 66 present calls, max score 91.43.
Top tissues by expression
174 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 91.43 | gold quality |
| bone marrow cell | CL:0002092 | 68.72 | silver quality |
| colonic epithelium | UBERON:0000397 | 63.25 | silver quality |
| granulocyte | CL:0000094 | 61.60 | gold quality |
| ventricular zone | UBERON:0003053 | 61.19 | gold quality |
| leukocyte | CL:0000738 | 56.06 | gold quality |
| lymph node | UBERON:0000029 | 55.92 | gold quality |
| vermiform appendix | UBERON:0001154 | 55.63 | gold quality |
| ganglionic eminence | UBERON:0004023 | 55.51 | silver quality |
| tonsil | UBERON:0002372 | 55.11 | gold quality |
| right testis | UBERON:0004534 | 54.80 | gold quality |
| left testis | UBERON:0004533 | 54.45 | gold quality |
| monocyte | CL:0000576 | 54.25 | gold quality |
| blood | UBERON:0000178 | 53.67 | gold quality |
| testis | UBERON:0000473 | 53.64 | gold quality |
| caecum | UBERON:0001153 | 52.20 | gold quality |
| gall bladder | UBERON:0002110 | 49.19 | gold quality |
| rectum | UBERON:0001052 | 48.39 | gold quality |
| olfactory segment of nasal mucosa | UBERON:0005386 | 47.92 | gold quality |
| islet of Langerhans | UBERON:0000006 | 47.41 | gold quality |
| small intestine Peyer’s patch | UBERON:0003454 | 47.30 | gold quality |
| small intestine | UBERON:0002108 | 46.90 | gold quality |
| bone marrow | UBERON:0002371 | 46.89 | silver quality |
| spleen | UBERON:0002106 | 46.82 | gold quality |
| adrenal gland | UBERON:0002369 | 46.34 | gold quality |
| adrenal tissue | UBERON:0018303 | 46.12 | silver quality |
| right lobe of liver | UBERON:0001114 | 45.06 | silver quality |
| anatomical system | UBERON:0000467 | 45.01 | gold quality |
| pancreas | UBERON:0001264 | 44.83 | gold quality |
| stomach | UBERON:0000945 | 44.73 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 0.32 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): BENTA disease, immunodeficiency 11b with atopic dermatitis, severe combined immunodeficiency due to CARD11 deficiency