CARS1-AS1

Summary

CARS1-AS1 (CARS1 antisense RNA 1, HGNC:40125) is a long non-coding RNA gene on chromosome 11p15.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40125
Approved symbol	CARS1-AS1
Name	CARS1 antisense RNA 1
Location	11p15.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000247473
Ensembl biotype	lncRNA
Entrez	100852407
RNAcentral	URS0000502FAC — lncRNA, 2664 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000499962, ENST00000630527

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499962 — 2 exons

Exon	Start	End
ENSE00001974217	3029394	3031576
ENSE00001979579	3040780	3041260

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 80.12.

Top tissues by expression

93 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.12	silver quality
bone marrow cell	CL:0002092	65.01	silver quality
sural nerve	UBERON:0015488	64.12	silver quality
skeletal muscle tissue	UBERON:0001134	63.01	silver quality
tonsil	UBERON:0002372	60.10	silver quality
bone marrow	UBERON:0002371	57.51	silver quality
blood	UBERON:0000178	53.02	silver quality
testis	UBERON:0000473	51.70	gold quality
left testis	UBERON:0004533	51.60	gold quality
cerebellar hemisphere	UBERON:0002245	51.32	silver quality
corpus callosum	UBERON:0002336	51.08	gold quality
monocyte	CL:0000576	50.14	silver quality
right testis	UBERON:0004534	49.70	gold quality
islet of Langerhans	UBERON:0000006	49.32	silver quality
calcaneal tendon	UBERON:0003701	49.26	silver quality
liver	UBERON:0002107	48.71	silver quality
lymph node	UBERON:0000029	47.70	silver quality
duodenum	UBERON:0002114	47.54	silver quality
kidney	UBERON:0002113	47.33	silver quality
urinary bladder	UBERON:0001255	47.10	silver quality
muscle of leg	UBERON:0001383	46.96	silver quality
gastrocnemius	UBERON:0001388	46.62	silver quality
gall bladder	UBERON:0002110	46.40	gold quality
uterine cervix	UBERON:0000002	45.86	silver quality
cortex of kidney	UBERON:0001225	45.78	silver quality
prefrontal cortex	UBERON:0000451	45.15	silver quality
multicellular organism	UBERON:0000468	44.87	gold quality
adenohypophysis	UBERON:0002196	44.54	gold quality
lung	UBERON:0002048	44.13	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	43.77	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.