CASK-AS1

Summary

CASK-AS1 (CASK antisense RNA 1, HGNC:40126) is a long non-coding RNA gene on chromosome Xp11.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40126
Approved symbol	CASK-AS1
Name	CASK antisense RNA 1
Location	Xp11.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233033
Ensembl biotype	lncRNA
Entrez	100873928
RNAcentral	URS0002853B1C — lncRNA, 2789 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000451126

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000451126 — 2 exons

Exon	Start	End
ENSE00001739690	41520036	41520366
ENSE00001780150	41522153	41522336

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 81.74.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.74	gold quality
ganglionic eminence	UBERON:0004023	77.96	gold quality
cortical plate	UBERON:0005343	73.01	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.94	gold quality
bone marrow cell	CL:0002092	68.67	silver quality
colonic epithelium	UBERON:0000397	66.57	silver quality
skeletal muscle tissue	UBERON:0001134	63.34	gold quality
gall bladder	UBERON:0002110	62.71	gold quality
lymph node	UBERON:0000029	62.67	gold quality
left coronary artery	UBERON:0001626	62.44	gold quality
popliteal artery	UBERON:0002250	62.29	gold quality
tibial artery	UBERON:0007610	62.26	gold quality
ectocervix	UBERON:0012249	61.85	gold quality
left ovary	UBERON:0002119	61.78	gold quality
ascending aorta	UBERON:0001496	61.30	gold quality
vagina	UBERON:0000996	61.24	gold quality
ovary	UBERON:0000992	60.92	gold quality
thoracic aorta	UBERON:0001515	60.70	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.92	gold quality
myometrium	UBERON:0001296	59.71	gold quality
duodenum	UBERON:0002114	58.84	gold quality
body of uterus	UBERON:0009853	58.66	gold quality
tibial nerve	UBERON:0001323	58.50	gold quality
right ovary	UBERON:0002118	58.37	gold quality
prostate gland	UBERON:0002367	58.28	gold quality
right uterine tube	UBERON:0001302	58.25	gold quality
skin of abdomen	UBERON:0001416	58.24	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.16	gold quality
descending thoracic aorta	UBERON:0002345	57.94	gold quality
cortex of kidney	UBERON:0001225	57.89	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.