CATIP-AS1

Summary

CATIP-AS1 (CATIP antisense RNA 1, HGNC:41080) is a long non-coding RNA gene on chromosome 2q35.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41080
Approved symbol	CATIP-AS1
Name	CATIP antisense RNA 1
Location	2q35
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225062
Ensembl biotype	lncRNA
Entrez	101928513
RNAcentral	URS000075D700 — lncRNA, 547 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 4 lncRNA, 1 retained_intron

ENST00000425481, ENST00000441749, ENST00000828657, ENST00000828658, ENST00000828659

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425481 — 2 exons

Exon	Start	End
ENSE00001679783	218366927	218367322
ENSE00001784707	218366666	218366798

Expression profiles

Bgee: expression breadth ubiquitous, 155 present calls, max score 86.57.

FANTOM5 (CAGE): breadth broad, TPM avg 1.1352 / max 71.3364, expressed in 255 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
33957	0.4185	164
33956	0.2745	88
33955	0.2285	74
33953	0.1180	63
33954	0.0956	52

Top tissues by expression

236 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.57	silver quality
right lung	UBERON:0002167	75.70	gold quality
granulocyte	CL:0000094	73.88	gold quality
bone marrow cell	CL:0002092	73.39	gold quality
colonic epithelium	UBERON:0000397	72.05	gold quality
right lobe of thyroid gland	UBERON:0001119	71.55	gold quality
blood	UBERON:0000178	71.21	gold quality
left lobe of thyroid gland	UBERON:0001120	70.57	gold quality
upper lobe of left lung	UBERON:0008952	70.54	gold quality
right lobe of liver	UBERON:0001114	70.52	gold quality
upper lobe of lung	UBERON:0008948	69.60	gold quality
thyroid gland	UBERON:0002046	69.42	gold quality
leukocyte	CL:0000738	69.28	gold quality
monocyte	CL:0000576	69.09	gold quality
spleen	UBERON:0002106	67.59	gold quality
corpus epididymis	UBERON:0004359	66.29	gold quality
body of stomach	UBERON:0001161	66.27	gold quality
lung	UBERON:0002048	64.25	gold quality
stomach	UBERON:0000945	63.97	gold quality
adult mammalian kidney	UBERON:0000082	63.70	gold quality
left adrenal gland	UBERON:0001234	63.49	gold quality
liver	UBERON:0002107	63.42	gold quality
left adrenal gland cortex	UBERON:0035825	63.27	gold quality
right adrenal gland	UBERON:0001233	63.05	gold quality
body of pancreas	UBERON:0001150	62.98	gold quality
caput epididymis	UBERON:0004358	62.30	gold quality
left uterine tube	UBERON:0001303	61.80	gold quality
prostate gland	UBERON:0002367	61.62	gold quality
adrenal gland	UBERON:0002369	61.54	gold quality
pancreas	UBERON:0001264	61.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.39

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long non-coding RNA CATIP antisense RNA 1 (lncRNA CATIP-AS1) downregulation contributes to the progression and metastasis of thyroid cancer via epithelial-mesenchymal transition (EMT) pathway. (PMID:35264071)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.