CAVIN2-AS1

Summary

CAVIN2-AS1 (CAVIN2 and TMEFF2 antisense RNA 1, HGNC:40517) is a long non-coding RNA gene on chromosome 2q32.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40517
Approved symbol	CAVIN2-AS1
Name	CAVIN2 and TMEFF2 antisense RNA 1
Location	2q32.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	LOC105373813
Ensembl gene	ENSG00000233766
Ensembl biotype	lncRNA
Entrez	105373813
RNAcentral	URS00026A2308 — lncRNA, 18347 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 25 — 25 lncRNA

ENST00000424116, ENST00000428980, ENST00000594023, ENST00000594591, ENST00000594798, ENST00000595918, ENST00000596486, ENST00000597204, ENST00000598327, ENST00000599681, ENST00000602099, ENST00000609865, ENST00000609952, ENST00000625221, ENST00000625555, ENST00000628836, ENST00000629279, ENST00000630824, ENST00000792812, ENST00000792813, ENST00000792814, ENST00000792815, ENST00000792816, ENST00000792817, ENST00000792818

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424116 — 3 exons

Exon	Start	End
ENSE00001634683	192034694	192034885
ENSE00001696751	192036685	192037121
ENSE00004175091	191846531	191846771

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 93.82.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6826 / max 198.5498, expressed in 183 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
24381	0.3449	133
24391	0.2585	29
24380	0.0791	39

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	93.82	gold quality
bone marrow cell	CL:0002092	84.87	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.63	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.99	gold quality
colonic epithelium	UBERON:0000397	74.11	gold quality
right lobe of thyroid gland	UBERON:0001119	74.08	gold quality
thyroid gland	UBERON:0002046	73.93	gold quality
left lobe of thyroid gland	UBERON:0001120	73.71	gold quality
apex of heart	UBERON:0002098	73.38	gold quality
heart left ventricle	UBERON:0002084	68.47	gold quality
right atrium auricular region	UBERON:0006631	67.56	gold quality
heart	UBERON:0000948	67.06	gold quality
sural nerve	UBERON:0015488	66.20	gold quality
adrenal tissue	UBERON:0018303	64.40	gold quality
bone marrow	UBERON:0002371	62.12	gold quality
urinary bladder	UBERON:0001255	61.36	gold quality
muscle layer of sigmoid colon	UBERON:0035805	60.90	gold quality
calcaneal tendon	UBERON:0003701	59.51	gold quality
monocyte	CL:0000576	59.29	gold quality
leukocyte	CL:0000738	59.27	gold quality
cortical plate	UBERON:0005343	59.01	gold quality
esophagus mucosa	UBERON:0002469	58.94	gold quality
esophagus	UBERON:0001043	58.69	gold quality
colon	UBERON:0001155	58.16	gold quality
lung	UBERON:0002048	58.10	gold quality
lower esophagus	UBERON:0013473	57.90	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	57.88	gold quality
lower esophagus muscularis layer	UBERON:0035833	57.87	gold quality
skeletal muscle tissue	UBERON:0001134	57.47	silver quality
upper lobe of left lung	UBERON:0008952	57.29	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	7.18
E-ANND-3	no	4.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.