CBR1-AS1
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Summary
CBR1-AS1 (CBR1 antisense RNA 1, HGNC:55777) is a long non-coding RNA gene on chromosome 21q22.12.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:55777 |
| Approved symbol | CBR1-AS1 |
| Name | CBR1 antisense RNA 1 |
| Location | 21q22.12 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000230212 |
| Ensembl biotype | lncRNA |
| Entrez | 100133286 |
| RNAcentral | URS00000E1B96 — lncRNA, 1221 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 lncRNA
ENST00000415147
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000415147 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001597545 | 36075531 | 36075602 |
| ENSE00002675369 | 36074881 | 36074967 |
Expression profiles
Bgee: expression breadth ubiquitous, 126 present calls, max score 86.97.
Top tissues by expression
126 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 86.97 | gold quality |
| sural nerve | UBERON:0015488 | 85.72 | gold quality |
| calcaneal tendon | UBERON:0003701 | 74.74 | gold quality |
| minor salivary gland | UBERON:0001830 | 67.98 | gold quality |
| saliva-secreting gland | UBERON:0001044 | 67.56 | gold quality |
| duodenum | UBERON:0002114 | 65.34 | gold quality |
| corpus callosum | UBERON:0002336 | 64.38 | gold quality |
| esophagus mucosa | UBERON:0002469 | 63.93 | gold quality |
| lower esophagus mucosa | UBERON:0035834 | 63.22 | gold quality |
| placenta | UBERON:0001987 | 63.16 | gold quality |
| cortical plate | UBERON:0005343 | 62.08 | gold quality |
| ventricular zone | UBERON:0003053 | 61.12 | gold quality |
| skin of abdomen | UBERON:0001416 | 60.96 | gold quality |
| liver | UBERON:0002107 | 60.81 | gold quality |
| stromal cell of endometrium | CL:0002255 | 60.51 | gold quality |
| zone of skin | UBERON:0000014 | 60.40 | gold quality |
| ectocervix | UBERON:0012249 | 60.29 | gold quality |
| skin of leg | UBERON:0001511 | 60.01 | gold quality |
| C1 segment of cervical spinal cord | UBERON:0006469 | 59.99 | gold quality |
| right lobe of liver | UBERON:0001114 | 59.59 | gold quality |
| urinary bladder | UBERON:0001255 | 59.45 | gold quality |
| Ammon’s horn | UBERON:0001954 | 59.32 | gold quality |
| esophagus | UBERON:0001043 | 58.90 | gold quality |
| vagina | UBERON:0000996 | 58.69 | gold quality |
| prefrontal cortex | UBERON:0000451 | 58.60 | gold quality |
| mucosa of stomach | UBERON:0001199 | 58.49 | gold quality |
| ganglionic eminence | UBERON:0004023 | 58.43 | gold quality |
| caudate nucleus | UBERON:0001873 | 58.11 | gold quality |
| putamen | UBERON:0001874 | 58.08 | gold quality |
| cerebellar hemisphere | UBERON:0002245 | 57.89 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | yes | 3.31 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with RUNX1