CCDC146-AS1

Summary

CCDC146-AS1 (CCDC146 antisense RNA 1, HGNC:58425) is a long non-coding RNA gene on chromosome 7q11.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58425
Approved symbol	CCDC146-AS1
Name	CCDC146 antisense RNA 1
Location	7q11.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250990
Ensembl biotype	lncRNA
Entrez	105375359

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000476561

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000476561 — 4 exons

Exon	Start	End
ENSE00001824991	77257201	77257255
ENSE00001890765	77246340	77246487
ENSE00001940927	77257907	77258123
ENSE00001948526	77255326	77255475

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 95.18.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.18	gold quality
right uterine tube	UBERON:0001302	83.96	gold quality
ventricular zone	UBERON:0003053	73.44	gold quality
lower esophagus mucosa	UBERON:0035834	70.12	gold quality
endometrium	UBERON:0001295	69.80	gold quality
minor salivary gland	UBERON:0001830	69.19	gold quality
saliva-secreting gland	UBERON:0001044	69.05	gold quality
skin of abdomen	UBERON:0001416	68.79	gold quality
fallopian tube	UBERON:0003889	68.70	gold quality
corpus callosum	UBERON:0002336	68.64	gold quality
smooth muscle tissue	UBERON:0001135	68.45	gold quality
colonic epithelium	UBERON:0000397	68.22	gold quality
zone of skin	UBERON:0000014	67.98	gold quality
right ovary	UBERON:0002118	67.61	gold quality
esophagus mucosa	UBERON:0002469	67.59	gold quality
skin of leg	UBERON:0001511	67.23	gold quality
esophagus	UBERON:0001043	66.95	gold quality
vagina	UBERON:0000996	66.80	gold quality
tibial nerve	UBERON:0001323	66.79	gold quality
duodenum	UBERON:0002114	66.75	gold quality
rectum	UBERON:0001052	66.28	gold quality
lower esophagus	UBERON:0013473	66.13	gold quality
lower esophagus muscularis layer	UBERON:0035833	66.09	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	65.81	gold quality
gall bladder	UBERON:0002110	65.73	gold quality
myometrium	UBERON:0001296	65.50	gold quality
thyroid gland	UBERON:0002046	65.50	gold quality
uterine cervix	UBERON:0000002	65.49	gold quality
tonsil	UBERON:0002372	65.31	gold quality
left lobe of thyroid gland	UBERON:0001120	65.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.74

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.