CCDC18-AS1

Summary

CCDC18-AS1 (CCDC18 antisense RNA 1, HGNC:52262) is a long non-coding RNA gene on chromosome 1p22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52262
Approved symbol	CCDC18-AS1
Name	CCDC18 antisense RNA 1
Location	1p22.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000440778.1
Ensembl gene	ENSG00000223745
Ensembl biotype	lncRNA
Entrez	100131564
RNAcentral	URS0000759C7B — lncRNA, 4033 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 39 — 39 lncRNA

ENST00000411670, ENST00000413606, ENST00000414430, ENST00000415150, ENST00000421202, ENST00000424517, ENST00000427669, ENST00000429859, ENST00000432741, ENST00000436200, ENST00000438777, ENST00000440778, ENST00000442860, ENST00000445076, ENST00000446528, ENST00000447577, ENST00000449305, ENST00000450843, ENST00000451302, ENST00000452347, ENST00000455474, ENST00000457025, ENST00000457387, ENST00000602488, ENST00000653362, ENST00000655606, ENST00000657560, ENST00000659026, ENST00000661111, ENST00000668257, ENST00000669506, ENST00000670231, ENST00000832692, ENST00000832693, ENST00000832694, ENST00000832695, ENST00000832696, ENST00000832697, ENST00000832698

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411670 — 8 exons

Exon	Start	End
ENSE00001673809	93339156	93339274
ENSE00001679477	93339649	93339679
ENSE00001681411	93339357	93339536
ENSE00001724047	93326602	93326662
ENSE00001746428	93325769	93325895
ENSE00001773770	93340458	93340510
ENSE00001799768	93345724	93345803
ENSE00001805870	93324706	93324729

Expression profiles

Bgee: expression breadth ubiquitous, 248 present calls, max score 98.95.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 13.0822 / max 220.2752, expressed in 1704 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
13305	12.9912	1703
13306	0.0910	28

Top tissues by expression

253 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus epididymis	UBERON:0004359	98.95	gold quality
right uterine tube	UBERON:0001302	98.75	gold quality
caput epididymis	UBERON:0004358	97.75	gold quality
cauda epididymis	UBERON:0004360	97.09	gold quality
oviduct epithelium	UBERON:0004804	97.05	gold quality
kidney epithelium	UBERON:0004819	96.59	gold quality
cardia of stomach	UBERON:0001162	96.36	gold quality
thymus	UBERON:0002370	96.32	gold quality
pituitary gland	UBERON:0000007	96.30	gold quality
renal medulla	UBERON:0000362	96.25	gold quality
ileal mucosa	UBERON:0000331	95.93	gold quality
nipple	UBERON:0002030	95.91	gold quality
adenohypophysis	UBERON:0002196	95.79	gold quality
sural nerve	UBERON:0015488	95.51	gold quality
upper arm skin	UBERON:0004263	95.32	gold quality
pylorus	UBERON:0001166	95.31	gold quality
left lobe of thyroid gland	UBERON:0001120	94.96	gold quality
trigeminal ganglion	UBERON:0001675	94.93	gold quality
thyroid gland	UBERON:0002046	94.89	gold quality
superficial temporal artery	UBERON:0001614	94.60	gold quality
fallopian tube	UBERON:0003889	94.45	gold quality
cardiac muscle of right atrium	UBERON:0003379	94.28	silver quality
left ovary	UBERON:0002119	94.15	gold quality
tibial nerve	UBERON:0001323	94.09	gold quality
dorsal root ganglion	UBERON:0000044	94.06	gold quality
corpus callosum	UBERON:0002336	93.93	gold quality
right lobe of thyroid gland	UBERON:0001119	93.91	gold quality
trabecular bone tissue	UBERON:0002483	93.70	gold quality
adrenal cortex	UBERON:0001235	93.59	gold quality
right adrenal gland cortex	UBERON:0035827	93.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Quantitative Expression of SFN, lncRNA CCDC18-AS1, and lncRNA LINC01343 in Human Breast Cancer as the Regulator Biomarkers in a Novel ceRNA Network: Based on Bioinformatics and Experimental Analyses. (PMID:36160032)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.