CCDST

Summary

CCDST (cervical cancer associated DHX9 suppressive transcript, HGNC:55988) is a long non-coding RNA gene on chromosome 1q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55988
Approved symbol	CCDST
Name	cervical cancer associated DHX9 suppressive transcript
Location	1q21.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AL589986.2, lnc-CCDST
Ensembl gene	ENSG00000236427
Ensembl biotype	lncRNA
Entrez	112268240, 339400
RNAcentral	URS000075D18A — lncRNA, 4112 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 40 — 40 lncRNA

ENST00000382265, ENST00000392688, ENST00000411804, ENST00000420707, ENST00000429352, ENST00000445097, ENST00000593011, ENST00000628475, ENST00000629331, ENST00000630125, ENST00000653548, ENST00000655109, ENST00000658099, ENST00000659844, ENST00000664213, ENST00000665223, ENST00000666686, ENST00000669062, ENST00000669830, ENST00000759267, ENST00000759269, ENST00000759270, ENST00000759271, ENST00000759272, ENST00000759273, ENST00000759274, ENST00000759275, ENST00000759276, ENST00000759277, ENST00000759278, ENST00000759279, ENST00000759280, ENST00000759281, ENST00000759282, ENST00000759283, ENST00000759284, ENST00000759285, ENST00000759286, ENST00000759287, ENST00000774927

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000382265 — 3 exons

Exon	Start	End
ENSE00001491493	152269417	152271094
ENSE00001670564	152251653	152251758
ENSE00001805770	152249003	152249012

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 92.67.

FANTOM5 (CAGE): breadth broad, TPM avg 1.6309 / max 96.4592, expressed in 617 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
5287	1.2056	532
5286	0.2171	79
5285	0.1808	71
5284	0.0275	7

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.67	gold quality
lower esophagus mucosa	UBERON:0035834	76.43	gold quality
quadriceps femoris	UBERON:0001377	69.42	gold quality
right testis	UBERON:0004534	69.32	gold quality
esophagus mucosa	UBERON:0002469	68.95	gold quality
left testis	UBERON:0004533	68.70	gold quality
testis	UBERON:0000473	68.19	gold quality
cerebellar vermis	UBERON:0004720	67.75	gold quality
adrenal tissue	UBERON:0018303	64.28	gold quality
skeletal muscle tissue	UBERON:0001134	64.07	silver quality
lymph node	UBERON:0000029	63.39	gold quality
thymus	UBERON:0002370	63.39	silver quality
esophagus	UBERON:0001043	62.84	gold quality
calcaneal tendon	UBERON:0003701	62.57	gold quality
monocyte	CL:0000576	60.93	gold quality
sural nerve	UBERON:0015488	60.53	gold quality
islet of Langerhans	UBERON:0000006	60.20	gold quality
vagina	UBERON:0000996	59.42	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.78	gold quality
bone marrow	UBERON:0002371	58.72	gold quality
liver	UBERON:0002107	58.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.11	gold quality
tonsil	UBERON:0002372	58.08	gold quality
prefrontal cortex	UBERON:0000451	57.60	gold quality
heart left ventricle	UBERON:0002084	57.30	gold quality
smooth muscle tissue	UBERON:0001135	56.49	gold quality
gastrocnemius	UBERON:0001388	55.86	gold quality
heart	UBERON:0000948	55.68	gold quality
pancreas	UBERON:0001264	54.83	gold quality
kidney	UBERON:0002113	54.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.