CCN2-AS1

Summary

CCN2-AS1 (CCN2 antisense RNA 1, HGNC:40164) is a long non-coding RNA gene on chromosome 6q23.2.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40164
Approved symbol	CCN2-AS1
Name	CCN2 antisense RNA 1
Location	6q23.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	AL133346.1
Ensembl gene	ENSG00000227220
Entrez	122152366
RNAcentral	URS00026A1ABD — lncRNA, 3766 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 92.02.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	92.02	gold quality
colonic epithelium	UBERON:0000397	80.68	gold quality
sural nerve	UBERON:0015488	79.56	gold quality
left uterine tube	UBERON:0001303	73.62	gold quality
cortical plate	UBERON:0005343	73.12	gold quality
mucosa of stomach	UBERON:0001199	72.41	gold quality
urinary bladder	UBERON:0001255	70.05	gold quality
bone marrow cell	CL:0002092	69.18	silver quality
lower esophagus muscularis layer	UBERON:0035833	68.99	gold quality
lower esophagus	UBERON:0013473	68.94	gold quality
body of uterus	UBERON:0009853	68.31	gold quality
ganglionic eminence	UBERON:0004023	67.88	gold quality
thoracic aorta	UBERON:0001515	67.76	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	67.76	gold quality
ascending aorta	UBERON:0001496	67.26	gold quality
ventricular zone	UBERON:0003053	67.09	gold quality
descending thoracic aorta	UBERON:0002345	66.61	gold quality
stromal cell of endometrium	CL:0002255	66.04	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	65.68	gold quality
myometrium	UBERON:0001296	65.46	gold quality
tibial artery	UBERON:0007610	65.20	gold quality
popliteal artery	UBERON:0002250	65.15	gold quality
fallopian tube	UBERON:0003889	64.81	gold quality
right atrium auricular region	UBERON:0006631	64.68	gold quality
cortex of kidney	UBERON:0001225	64.67	gold quality
bone marrow	UBERON:0002371	64.46	silver quality
hindlimb stylopod muscle	UBERON:0004252	64.46	gold quality
muscle layer of sigmoid colon	UBERON:0035805	64.00	gold quality
left coronary artery	UBERON:0001626	63.89	gold quality
skeletal muscle tissue	UBERON:0001134	62.76	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	15.08
E-ANND-3	yes	4.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.