CD63-AS1

Summary

CD63-AS1 (CD63 antisense RNA 1, HGNC:55455) is a long non-coding RNA gene on chromosome 12q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55455
Approved symbol	CD63-AS1
Name	CD63 antisense RNA 1
Location	12q13.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	CEAM
Ensembl gene	ENSG00000258056
Ensembl biotype	lncRNA
Entrez	105369779
RNAcentral	URS00026A260F — lncRNA, 1453 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000552576

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000552576 — 2 exons

Exon	Start	End
ENSE00002381542	55729662	55730857
ENSE00004061272	55729078	55729355

Expression profiles

Bgee: expression breadth ubiquitous, 165 present calls, max score 89.35.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.5179 / max 30.1615, expressed in 1500 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
125981	2.0879	1107
125982	1.1302	705
125983	0.2999	142

Top tissues by expression

236 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	89.35	gold quality
apex of heart	UBERON:0002098	87.37	gold quality
spinal cord	UBERON:0002240	86.55	gold quality
right atrium auricular region	UBERON:0006631	83.32	gold quality
gastrocnemius	UBERON:0001388	82.94	gold quality
muscle of leg	UBERON:0001383	82.33	gold quality
buccal mucosa cell	CL:0002336	82.24	silver quality
heart left ventricle	UBERON:0002084	81.93	gold quality
hypothalamus	UBERON:0001898	81.65	gold quality
cardiac atrium	UBERON:0002081	81.44	gold quality
hindlimb stylopod muscle	UBERON:0004252	81.43	gold quality
amygdala	UBERON:0001876	81.38	gold quality
cardiac ventricle	UBERON:0002082	81.07	gold quality
tendon of biceps brachii	UBERON:0008188	80.72	silver quality
islet of Langerhans	UBERON:0000006	80.66	gold quality
putamen	UBERON:0001874	80.10	gold quality
heart	UBERON:0000948	79.53	gold quality
substantia nigra	UBERON:0002038	79.35	gold quality
anterior cingulate cortex	UBERON:0009835	79.25	gold quality
lower esophagus muscularis layer	UBERON:0035833	78.82	gold quality
lower esophagus	UBERON:0013473	78.78	gold quality
monocyte	CL:0000576	78.18	gold quality
muscle layer of sigmoid colon	UBERON:0035805	78.16	gold quality
caudate nucleus	UBERON:0001873	78.12	gold quality
leukocyte	CL:0000738	78.08	gold quality
right lobe of thyroid gland	UBERON:0001119	77.56	gold quality
pancreas	UBERON:0001264	77.42	gold quality
adenohypophysis	UBERON:0002196	77.42	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	77.38	gold quality
nucleus accumbens	UBERON:0001882	77.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.86

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• CEAM is a mitochondrial-localized, amyloid-like motif-containing microprotein expressed in human cardiomyocytes. (PMID:39388734)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.