CD72

Summary

CD72 (CD72 molecule, HGNC:1696) is a protein-coding gene on chromosome 9p13.3, encoding B-cell differentiation antigen CD72 (P21854). Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions.

Enables transmembrane signaling receptor activity. Involved in negative regulation of B cell receptor signaling pathway. Located in plasma membrane.

Source: NCBI Gene 971 — RefSeq curated summary.

At a glance

• GWAS associations: 2
• Clinical variants (ClinVar): 50 total
• Druggable target: yes
• MANE Select transcript: NM_001782

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:1696
Approved symbol	CD72
Name	CD72 molecule
Location	9p13.3
Locus type	gene with protein product
Status	Approved
Aliases	LYB2, CD72b
Ensembl gene	ENSG00000137101
Ensembl biotype	protein_coding
OMIM	107272
Entrez	971

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 6 protein_coding_CDS_not_defined, 4 protein_coding

ENST00000259633, ENST00000378430, ENST00000378431, ENST00000396757, ENST00000463720, ENST00000465754, ENST00000470387, ENST00000477364, ENST00000482121, ENST00000490239

RefSeq mRNA: 1 — MANE Select: NM_001782 NM_001782

CCDS: CCDS6581

Canonical transcript exons

ENST00000259633 — 9 exons

Exon	Start	End
ENSE00001526158	35609982	35610300
ENSE00001526162	35618222	35618413
ENSE00003461777	35612848	35612993
ENSE00003474487	35615943	35616278
ENSE00003497440	35610602	35610753
ENSE00003545291	35618014	35618121
ENSE00003558541	35617176	35617247
ENSE00003633000	35611804	35611919
ENSE00003657273	35616600	35616689

Expression profiles

Bgee: expression breadth ubiquitous, 184 present calls, max score 96.69.

FANTOM5 (CAGE): breadth broad, TPM avg 2.9198 / max 223.3429, expressed in 800 samples.

FANTOM5 promoters (7 alternative TSS)

Promoter ID	TPM avg	Samples expressed
100585	1.2476	142
100590	0.9232	551
100589	0.5159	232
100587	0.0998	51
205472	0.0572	24
100591	0.0391	16
100586	0.0370	16

Top tissues by expression

285 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
spleen	UBERON:0002106	96.69	gold quality
lymph node	UBERON:0000029	91.58	gold quality
granulocyte	CL:0000094	91.14	gold quality
vermiform appendix	UBERON:0001154	90.48	gold quality
caecum	UBERON:0001153	83.40	gold quality
blood	UBERON:0000178	82.35	gold quality
bone marrow	UBERON:0002371	79.92	gold quality
tonsil	UBERON:0002372	79.88	gold quality
gall bladder	UBERON:0002110	79.80	gold quality
small intestine Peyer’s patch	UBERON:0003454	79.13	gold quality
superficial temporal artery	UBERON:0001614	77.27	gold quality
right uterine tube	UBERON:0001302	77.08	gold quality
right lung	UBERON:0002167	77.05	gold quality
adenohypophysis	UBERON:0002196	76.94	gold quality
right adrenal gland cortex	UBERON:0035827	75.80	gold quality
Brodmann (1909) area 10	UBERON:0013541	75.69	gold quality
bone marrow cell	CL:0002092	75.68	gold quality
right adrenal gland	UBERON:0001233	75.64	gold quality
leukocyte	CL:0000738	75.52	gold quality
epithelium of nasopharynx	UBERON:0001951	75.32	gold quality
descending thoracic aorta	UBERON:0002345	75.25	gold quality
small intestine	UBERON:0002108	75.22	gold quality
left adrenal gland cortex	UBERON:0035825	75.18	gold quality
islet of Langerhans	UBERON:0000006	74.78	gold quality
left adrenal gland	UBERON:0001234	74.66	gold quality
type B pancreatic cell	CL:0000169	74.56	gold quality
mononuclear cell	CL:0000842	74.40	gold quality
monocyte	CL:0000576	74.39	gold quality
mucosa of stomach	UBERON:0001199	74.28	gold quality
endometrium epithelium	UBERON:0004811	73.94	gold quality

Single-cell (SCXA)

Detected in 8 experiment(s), a significant marker in 7.

Experiment	Marker?	Max mean expression
E-CURD-122	yes	67.72
E-HCAD-4	yes	55.16
E-CURD-112	yes	41.90
E-MTAB-9067	yes	17.11
E-ANND-3	yes	15.07
E-HCAD-10	yes	13.52
E-MTAB-9801	yes	5.43
E-MTAB-6386	no	1605.08

Regulation

Is transcription factor: no

Upstream regulators (CollecTRI, top): E2F1, PAX5, SPI1

miRNA regulators (miRDB)

15 targeting CD72, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-95-5P	99.89	72.17	3973
HSA-MIR-548AR-3P	99.85	71.26	3889
HSA-MIR-548AZ-3P	99.82	70.56	3549
HSA-MIR-548BC	99.82	70.61	3524
HSA-MIR-548E-3P	99.82	70.59	3514
HSA-MIR-548F-3P	99.82	70.59	3540
HSA-MIR-548A-3P	99.76	70.58	3524
HSA-MIR-148A-3P	99.74	73.77	1700
HSA-MIR-148B-3P	99.74	73.75	1700
HSA-MIR-152-3P	99.74	73.75	1703
HSA-MIR-6840-3P	98.68	65.95	1923
HSA-MIR-5088-3P	98.29	66.63	1310
HSA-MIR-6842-3P	98.07	66.33	1325
HSA-MIR-3652	97.71	65.43	1890
HSA-MIR-4430	97.47	65.61	1813

Literature-anchored findings (GeneRIF, showing 18)

• results indicated that the presence of CD72-*2 allele decreases risk for human systemic lupus erythematosus conferred by FCGR2B-232Thr, possibly by increasing the AS isoform of CD72 (PMID:15459183)
• CD72 is a key molecule in regulating mature B cell differentiation; CD72 signaling reduces the expression of X-box binding protein 1 in B cells (PMID:16047337)
• increased nucleotide mutation of CD72 mRNA accounts for the decreased expression level of CD72 in B cells, and it might be related to hyperactivity of B cells in patients with SLE (PMID:17121583)
• CD100-CD72 interaction can be the mechanism by which NK cell communicate with B cells. (PMID:17786190)
• CD72 polymorphisms are associated with age of appearing clinical manifestations in idiopathic thrombocytopenic purpura in Chinese patients. (PMID:18071878)
• Data show that ligation of CD72 with the BU40, or with rCD100 negatively regulates KIT-mediated mast cell proliferation, chemotaxis, and chemokine production. (PMID:20100931)
• CD72 mRNA expression level correlates with Sema4D expression in peripheral blood mononuclear cells in immune thrombocytopenia. (PMID:22111667)
• data demonstrated aberrant expression of CD72 exists on B cells of myasthenia gravis and multiple sclerosis patients and expression level of CD72 molecule has a significantly negative correlation with anti-AchR antibody levels in myasthenia gravis (PMID:23184497)
• regulates serum immunoglobulin leveln and disease resistance in systemic lupus erythematosus (PMID:23268649)
• CD72 expression on activated B cells of SLE patients was significantly lower than that of normal controls. sema3A enhanced CD72 expression of B cells, but it was still lower in SLE patients than in normal individuals. (PMID:24461079)
• Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis (PMID:26883681)
• Interferon-alpha-induced CD100 expression on naive CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction. (PMID:28222623)
• A regulatory role for CD72 expression on B cells and increased soluble CD72 in primary Sjogren’s syndrome. (PMID:32306893)
• CD40 and CD72 expression and prognostic values among children with systemic lupus erythematosus: a case-control study. (PMID:32700598)
• Blockage of CD72 reduces B cell proliferation in immune thrombocytopenic purpura, involving interleukin 1 and macrophage migration inhibitory factor secretion. (PMID:36326455)
• CD72-semaphorin3A axis: A new regulatory pathway in systemic lupus erythematosus. (PMID:36470209)
• CD72 is a pan-tumor antigen associated to pediatric acute leukemia. (PMID:37876342)
• CD72, a new immune checkpoint molecule, is a novel prognostic biomarker for kidney renal clear cell carcinoma. (PMID:37980541)

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Cd72	ENSMUSG00000028459
rattus_norvegicus	Cd72	ENSRNOG00000017485

Protein

Protein identifiers

B-cell differentiation antigen CD72 — P21854 (reviewed: P21854)

Alternative names: Lyb-2

All UniProt accessions (5): A0A6E1WA84, P21854, Q5T4Q7, Q5T4Q8, Q5TLG3

UniProt curated annotations — full annotation on UniProt →

Function. Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis.

Subunit / interactions. Homodimer; disulfide-linked. Associates with CD5. Interacts (tyrosine phosphorylated) with PTPN6/SHP-1.

Subcellular location. Membrane.

Tissue specificity. Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Post-translational modifications. Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1.

RefSeq proteins (1): NP_001773* (*=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR001304	C-type_lectin-like	Domain
IPR016186	C-type_lectin-like/link_sf	Homologous_superfamily
IPR016187	CTDL_fold	Homologous_superfamily
IPR039689	CD72	Family

Pfam: PF00059

UniProt features (12 total): disulfide bond 3, topological domain 2, modified residue 2, chain 1, sequence variant 1, transmembrane region 1, domain 1, glycosylation site 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-P21854-F1	76.85	0.48

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (2): 7, 39

Disulfide bonds (3): 325–342, 233–244, 261–350

Glycosylation sites (1): 136

Function

Pathways and Gene Ontology

Reactome pathways

5 pathways

ID	Pathway
R-HSA-416700	Other semaphorin interactions
R-HSA-1266738	Developmental Biology
R-HSA-373755	Semaphorin interactions
R-HSA-422475	Axon guidance
R-HSA-9675108	Nervous system development

MSigDB gene sets: 340 (showing top): PID_BCR_5PATHWAY, GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8_TCELL_IFNAR_KO_DN, GOBP_REGULATION_OF_B_CELL_RECEPTOR_SIGNALING_PATHWAY, GOBP_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY, YAGI_AML_WITH_INV_16_TRANSLOCATION, GCANCTGNY_MYOD_Q6, REACTOME_OTHER_SEMAPHORIN_INTERACTIONS, GOBP_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY, MORI_IMMATURE_B_LYMPHOCYTE_UP, CAGCTG_AP4_Q5, GOBP_REGULATION_OF_IMMUNE_RESPONSE, MODULE_75, ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP, chr9p13, MODULE_410

GO Biological Process (2): cell adhesion (GO:0007155), negative regulation of B cell receptor signaling pathway (GO:0050859)

GO Molecular Function (4): transmembrane signaling receptor activity (GO:0004888), signaling receptor binding (GO:0005102), carbohydrate binding (GO:0030246), protein binding (GO:0005515)

GO Cellular Component (2): plasma membrane (GO:0005886), membrane (GO:0016020)

Reactome top-level categories

Rollup of top-4 pathways:

Category	Pathways
Semaphorin interactions	1
Axon guidance	1
Nervous system development	1
Developmental Biology	1

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
binding	2
cellular process	1
B cell receptor signaling pathway	1
regulation of B cell receptor signaling pathway	1
negative regulation of antigen receptor-mediated signaling pathway	1
signaling receptor activity	1
protein binding	1
membrane	1
cell periphery	1
cellular anatomical structure	1

Protein interactions and networks

STRING

1248 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
CD72	SEMA4D	Q92854	998
CD72	CD5	P06127	992
CD72	PLXNB1	O43157	846
CD72	FCGR2B	P31994	803
CD72	CD22	P20273	795
CD72	PTPN6	P29350	719
CD72	SEMA4A	Q9H3S1	676
CD72	PLXNB2	O15031	624
CD72	CD79A	P11912	622
CD72	CD79B	P40259	586
CD72	FCRLA	Q7L513	572
CD72	CD19	P15391	552
CD72	CHIA	Q9BZP6	552
CD72	CD6	P30203	550
CD72	CR2	P20023	532

IntAct

54 interactions, top by confidence:

A	B	Type	Score
CD72	CGRRF1	psi-mi:“MI:0915”(physical association)	0.560
CD72	LHFPL5	psi-mi:“MI:0915”(physical association)	0.560
CD72	SPACA1	psi-mi:“MI:0915”(physical association)	0.560
CD72	ATP6AP2	psi-mi:“MI:0915”(physical association)	0.560
CD72	GRAMD1C	psi-mi:“MI:0915”(physical association)	0.560
CD72	BIK	psi-mi:“MI:0915”(physical association)	0.560
CD72	NRG1	psi-mi:“MI:0915”(physical association)	0.560
CD72	LSMEM2	psi-mi:“MI:0915”(physical association)	0.560
CD72	CREB3L1	psi-mi:“MI:0915”(physical association)	0.560
CD72	MS4A7	psi-mi:“MI:0915”(physical association)	0.560
CLDN7	CD72	psi-mi:“MI:0915”(physical association)	0.560
CD72	LRRC25	psi-mi:“MI:0915”(physical association)	0.560
CD72	GPR152	psi-mi:“MI:0915”(physical association)	0.560
CD72	MS4A3	psi-mi:“MI:0915”(physical association)	0.560
ATP6AP2	CD72	psi-mi:“MI:0915”(physical association)	0.560
SEMA4D	CD72	psi-mi:“MI:0407”(direct interaction)	0.440
HMGA1	CD72	psi-mi:“MI:0915”(physical association)	0.400
CD5	CD72	psi-mi:“MI:0915”(physical association)	0.400
CD72	TRUB1	psi-mi:“MI:0915”(physical association)	0.400
CD72	NCAM2	psi-mi:“MI:0915”(physical association)	0.400
FCGR2A	CD72	psi-mi:“MI:0915”(physical association)	0.400
FCGR1A	CD72	psi-mi:“MI:0915”(physical association)	0.400
CD72	CALML3	psi-mi:“MI:0914”(association)	0.350

BioGRID (33): CD72 (Reconstituted Complex), SIGLEC10 (Affinity Capture-MS), KLHL15 (Affinity Capture-MS), CALML3 (Affinity Capture-MS), CD72 (Two-hybrid), CD72 (Affinity Capture-Western), CD72 (Affinity Capture-Western), CD72 (Two-hybrid), CD72 (Two-hybrid), CD72 (Two-hybrid), MS4A3 (Two-hybrid), NRG1 (Two-hybrid), CREB3L1 (Two-hybrid), MS4A7 (Two-hybrid), LRRC25 (Two-hybrid)

ESM2 similar proteins: A4KWA1, D4AD02, O70156, O70215, P20937, P21854, P21855, P26715, P26717, P27471, P27811, P27812, P27814, P60883, Q149M0, Q2HXU8, Q2NL33, Q504P2, Q5QGZ9, Q60651, Q60652, Q60653, Q60654, Q60660, Q60682, Q64329, Q6QLQ4, Q6UXN8, Q6WRU0, Q80ZC8, Q8BRU4, Q8BWY2, Q8CJC7, Q8HY02, Q8HY04, Q8HY06, Q8MI05, Q8NC01, Q8VBX4, Q8VD98

Diamond homologs: A4KWA5, A4KWA8, O88713, O89335, P06734, P0CA63, P0CA64, P14370, P14371, P21854, P26715, Q0H8B9, Q5M9I1, Q64329, Q64335, Q65150, Q6ZS10, Q80XD9, Q8C1T8, Q8CJC7, Q8VI21, Q91V08, Q92478, Q925N7, Q9D676, Q9MZJ3, Q9R0Q8, Q9UHP7, P07307, P21855, P34927, P49300, P49301, Q69FH1, Q8HZR8, Q8IUN9, Q9BXN2, A4KWA6, A6QP79, D3W0D1

SIGNOR signaling

1 interactions.

A	Effect	B	Mechanism
PTPN6	down-regulates	CD72	dephosphorylation

Disease & clinical

Clinical variants and AI predictions

ClinVar

50 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	38
Likely benign	2
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

1423 predictions. Top by Δscore:

Variant	Effect	Δscore
9:35612846:A:AC	donor_gain	0.9900
9:35612847:C:CC	donor_gain	0.9900
9:35617174:A:AC	donor_gain	0.9900
9:35617175:C:CC	donor_gain	0.9900
9:35617245:CCG:C	acceptor_gain	0.9900
9:35617246:CG:C	acceptor_gain	0.9900
9:35617246:CGC:C	acceptor_gain	0.9900
9:35617248:C:CC	acceptor_gain	0.9900
9:35618076:TGA:T	donor_gain	0.9900
9:35619511:CCA:C	donor_gain	0.9900
9:35615937:GGATA:G	donor_loss	0.9800
9:35615938:GATA:G	donor_loss	0.9800
9:35615939:ATAC:A	donor_loss	0.9800
9:35615940:TA:T	donor_loss	0.9800
9:35615941:A:C	donor_loss	0.9800
9:35615942:CCTG:C	donor_gain	0.9800
9:35616594:A:AC	donor_gain	0.9800
9:35616595:C:CC	donor_gain	0.9800
9:35618220:AC:A	donor_gain	0.9800
9:35618221:CC:C	donor_gain	0.9800
9:35612915:T:A	donor_gain	0.9700
9:35616599:CAG:C	donor_gain	0.9700
9:35616599:CAGCG:C	donor_gain	0.9700
9:35616691:T:C	acceptor_gain	0.9700
9:35617247:GC:G	acceptor_loss	0.9700
9:35617248:CTGT:C	acceptor_loss	0.9700
9:35617249:T:C	acceptor_loss	0.9700
9:35618016:G:A	donor_gain	0.9700
9:35619506:CCTCA:C	donor_loss	0.9700
9:35619507:CTCAC:C	donor_loss	0.9700

AlphaMissense

2308 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
9:35612971:C:A	W237C	0.997
9:35612971:C:G	W237C	0.997
9:35612973:A:G	W237R	0.994
9:35612973:A:T	W237R	0.994
9:35612900:C:G	C261S	0.993
9:35612901:A:T	C261S	0.993
9:35618268:A:C	F12L	0.992
9:35618268:A:T	F12L	0.992
9:35618270:A:G	F12L	0.992
9:35610655:C:G	C350S	0.991
9:35610656:A:T	C350S	0.991
9:35611860:C:A	W298C	0.991
9:35611860:C:G	W298C	0.991
9:35610655:C:T	C350Y	0.987
9:35612899:A:C	C261W	0.986
9:35610654:A:C	C350W	0.985
9:35612900:C:T	C261Y	0.985
9:35612950:G:C	C244W	0.985
9:35612911:G:C	S257R	0.984
9:35612911:G:T	S257R	0.984
9:35612913:T:G	S257R	0.984
9:35612951:C:G	C244S	0.984
9:35612952:A:T	C244S	0.984
9:35612920:C:A	W254C	0.983
9:35612920:C:G	W254C	0.983
9:35612900:C:A	C261F	0.982
9:35612901:A:G	C261R	0.982
9:35612951:C:T	C244Y	0.982
9:35612952:A:G	C244R	0.982
9:35610656:A:G	C350R	0.977

dbSNP variants (sampled 300 via entrez): RS1000058731 (9:35638800 G>A,C), RS1000096557 (9:35632070 C>G), RS1000105675 (9:35640585 A>G), RS1000513122 (9:35610046 G>A,T), RS1000528127 (9:35615217 G>A), RS1000561031 (9:35640332 C>T), RS1000566923 (9:35610234 G>A,C,T), RS1000659432 (9:35637423 C>T), RS1000718185 (9:35646194 G>T), RS1000747793 (9:35645800 C>T), RS1000793277 (9:35629435 ATATG>A), RS1000816561 (9:35611344 C>T), RS1000968625 (9:35623323 G>A,C), RS1001093015 (9:35637250 C>T), RS1001103118 (9:35630451 C>G)

Disease associations

OMIM: gene MIM:107272 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

2 associations (top):

Study	Trait	p-value
GCST002709_10	Electroencephalogram traits	2.000000e-06
GCST006585_664	Blood protein levels	5.000000e-06

EFO canonical traits (2, from GWAS)

EFO ID	Trait name
EFO:0004357	electroencephalogram measurement
EFO:0006870	alpha wave measurement

Drugs & pharmacology

Drug and pharmacology data

Is drug target: yes

ChEMBL targets (1): CHEMBL5169122 (SINGLE PROTEIN)

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

29 total (human), top 29 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
GSK-J4	decreases expression	1
sotorasib	affects cotreatment, decreases expression	1
triphenyl phosphate	affects expression	1
bisphenol A	affects cotreatment, increases methylation	1
titanium dioxide	increases expression	1
terbufos	increases methylation	1
sodium arsenite	increases expression	1
S-(1,2-dichlorovinyl)cysteine	affects response to substance, increases expression	1
di-n-butylphosphoric acid	affects expression	1
ON 01910	decreases expression	1
trametinib	affects cotreatment, decreases expression	1
(+)-JQ1 compound	decreases expression	1
NVP-BKM120	affects cotreatment, decreases expression	1
Fulvestrant	affects cotreatment, increases methylation	1
Air Pollutants	decreases methylation, increases abundance	1
Arsenic	affects methylation	1
Atrazine	increases expression	1
Benzo(a)pyrene	decreases expression	1
Fonofos	increases methylation	1
Lipopolysaccharides	decreases expression, affects response to substance, increases expression	1
Nitrogen Dioxide	decreases methylation, increases abundance	1
Oxygen	increases expression	1
Parathion	increases methylation	1
Silicon Dioxide	decreases expression	1
Smoke	decreases expression	1
Tobacco Smoke Pollution	decreases expression	1
Antirheumatic Agents	decreases expression	1
Okadaic Acid	decreases expression	1
Permethrin	increases expression	1

ChEMBL screening assays

1 unique, capped per target: 1 binding

Representative assays (with source publication via chembl_document):

Assay ID	Type	Description	Source paper
CHEMBL5136271	Binding	Induction of CD72 degradation in human MINO cells at 100 nM measured after 8 hrs by proteomic analysis	Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton’s Tyrosine Kinase for the Treatment of Lymphoma. — J Med Chem

Cellosaurus cell lines

1 cell lines: 1 cancer cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_E1JS	HyCyte Daudi KO-hCD72	Cancer cell line	Male

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.