CDC42-AS1

Summary

CDC42-AS1 (CDC42 antisense RNA 1, HGNC:54314) is a long non-coding RNA gene on chromosome 1p36.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54314
Approved symbol	CDC42-AS1
Name	CDC42 antisense RNA 1
Location	1p36.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000285752
Ensembl biotype	lncRNA
Entrez	112268223
RNAcentral	URS0000DB9A2E — lncRNA, 2574 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000649486

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000649486 — 3 exons

Exon	Start	End
ENSE00003837678	22028317	22028682
ENSE00003838633	22052787	22052927
ENSE00003839013	22029801	22031867

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 86.52.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2065 / max 39.9712, expressed in 68 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
10911	0.2065	68

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.52	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.01	gold quality
body of pancreas	UBERON:0001150	75.85	gold quality
endometrium	UBERON:0001295	70.12	gold quality
granulocyte	CL:0000094	69.24	gold quality
pancreas	UBERON:0001264	69.09	gold quality
right uterine tube	UBERON:0001302	68.93	gold quality
spleen	UBERON:0002106	68.22	gold quality
right lobe of liver	UBERON:0001114	67.90	gold quality
right lobe of thyroid gland	UBERON:0001119	66.03	gold quality
lymph node	UBERON:0000029	65.78	gold quality
right ovary	UBERON:0002118	65.20	gold quality
thyroid gland	UBERON:0002046	65.06	gold quality
stromal cell of endometrium	CL:0002255	65.05	gold quality
pituitary gland	UBERON:0000007	64.96	gold quality
left lobe of thyroid gland	UBERON:0001120	64.94	gold quality
mucosa of transverse colon	UBERON:0004991	64.82	gold quality
cortical plate	UBERON:0005343	64.77	gold quality
right adrenal gland	UBERON:0001233	64.76	gold quality
right adrenal gland cortex	UBERON:0035827	64.40	gold quality
left ovary	UBERON:0002119	64.38	gold quality
liver	UBERON:0002107	64.30	gold quality
cortex of kidney	UBERON:0001225	64.23	gold quality
ovary	UBERON:0000992	64.20	gold quality
vermiform appendix	UBERON:0001154	64.10	gold quality
apex of heart	UBERON:0002098	63.41	gold quality
cerebellar cortex	UBERON:0002129	63.09	gold quality
cerebellar hemisphere	UBERON:0002245	63.08	gold quality
cerebellum	UBERON:0002037	63.01	gold quality
ventricular zone	UBERON:0003053	62.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.