CDC42-IT1

Summary

CDC42-IT1 (CDC42 intronic transcript 1, HGNC:41317) is a long non-coding RNA gene on chromosome 1p36.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41317
Approved symbol	CDC42-IT1
Name	CDC42 intronic transcript 1
Location	1p36.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230068
Ensembl biotype	lncRNA
Entrez	100874292
RNAcentral	URS0000390BA6 — lncRNA, 692 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000431803

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000431803 — 2 exons

Exon	Start	End
ENSE00001715139	22063998	22064199
ENSE00001737907	22059197	22059686

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 81.90.

Top tissues by expression

202 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.90	gold quality
bone marrow cell	CL:0002092	80.27	gold quality
trabecular bone tissue	UBERON:0002483	79.29	gold quality
corpus epididymis	UBERON:0004359	78.66	gold quality
mucosa of paranasal sinus	UBERON:0005030	77.86	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.01	gold quality
oral cavity	UBERON:0000167	76.74	gold quality
cauda epididymis	UBERON:0004360	75.57	gold quality
caput epididymis	UBERON:0004358	74.81	gold quality
superficial temporal artery	UBERON:0001614	73.24	gold quality
buccal mucosa cell	CL:0002336	72.55	silver quality
bronchial epithelial cell	CL:0002328	71.16	gold quality
bronchus	UBERON:0002185	70.27	gold quality
bone marrow	UBERON:0002371	69.53	gold quality
colonic epithelium	UBERON:0000397	68.28	silver quality
jejunal mucosa	UBERON:0000399	67.60	gold quality
upper leg skin	UBERON:0004262	66.17	gold quality
skin of hip	UBERON:0001554	65.03	gold quality
lower lobe of lung	UBERON:0008949	64.69	silver quality
ganglionic eminence	UBERON:0004023	64.51	gold quality
germinal epithelium of ovary	UBERON:0001304	64.50	silver quality
parietal pleura	UBERON:0002400	63.57	gold quality
cartilage tissue	UBERON:0002418	63.27	silver quality
penis	UBERON:0000989	62.51	gold quality
mucosa of sigmoid colon	UBERON:0004993	62.43	gold quality
blood	UBERON:0000178	62.29	gold quality
palpebral conjunctiva	UBERON:0001812	62.17	gold quality
visceral pleura	UBERON:0002401	61.98	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.55	gold quality
mammalian vulva	UBERON:0000997	59.78	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.