CDH4-AS1

Summary

CDH4-AS1 (CDH4 antisense RNA 1, HGNC:40139) is a long non-coding RNA gene on chromosome 20q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40139
Approved symbol	CDH4-AS1
Name	CDH4 antisense RNA 1
Location	20q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225106
Ensembl biotype	lncRNA
Entrez	139355210
RNAcentral	URS0002A4008D — lncRNA, 1066 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000442888, ENST00000447909

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000442888 — 3 exons

Exon	Start	End
ENSE00001702800	61740471	61740887
ENSE00001708486	61738863	61739090
ENSE00001712561	61754992	61755025

Expression profiles

Bgee: expression breadth broad, 72 present calls, max score 72.56.

Top tissues by expression

72 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.56	gold quality
liver	UBERON:0002107	64.59	silver quality
skin of leg	UBERON:0001511	61.00	gold quality
right hemisphere of cerebellum	UBERON:0014890	59.12	gold quality
monocyte	CL:0000576	59.10	gold quality
prefrontal cortex	UBERON:0000451	58.52	gold quality
cerebellar hemisphere	UBERON:0002245	57.48	gold quality
zone of skin	UBERON:0000014	56.73	gold quality
frontal cortex	UBERON:0001870	56.67	gold quality
anterior cingulate cortex	UBERON:0009835	56.12	gold quality
gall bladder	UBERON:0002110	55.55	gold quality
cerebral cortex	UBERON:0000956	55.52	gold quality
Brodmann (1909) area 9	UBERON:0013540	55.46	gold quality
Ammon’s horn	UBERON:0001954	54.93	gold quality
superior frontal gyrus	UBERON:0002661	54.91	gold quality
right frontal lobe	UBERON:0002810	54.88	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	54.24	gold quality
brain	UBERON:0000955	53.37	gold quality
stromal cell of endometrium	CL:0002255	52.89	silver quality
multicellular organism	UBERON:0000468	52.20	gold quality
temporal lobe	UBERON:0001871	51.12	gold quality
endometrium	UBERON:0001295	50.81	silver quality
amygdala	UBERON:0001876	50.57	gold quality
subcutaneous adipose tissue	UBERON:0002190	50.27	gold quality
urinary bladder	UBERON:0001255	50.16	gold quality
myometrium	UBERON:0001296	50.11	gold quality
skin of abdomen	UBERON:0001416	49.90	gold quality
lymph node	UBERON:0000029	49.47	silver quality
thoracic mammary gland	UBERON:0005200	48.15	gold quality
adipose tissue	UBERON:0001013	48.01	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.