CDK5R2-AS1

Summary

CDK5R2-AS1 (CDK5R2 antisense RNA 1, HGNC:55677) is a long non-coding RNA gene on chromosome 2q35.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55677
Approved symbol	CDK5R2-AS1
Name	CDK5R2 antisense RNA 1
Location	2q35
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235024
Ensembl biotype	lncRNA
Entrez	121847983
RNAcentral	URS0002A5132C — lncRNA, 3167 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000419511, ENST00000429343, ENST00000715606, ENST00000715607, ENST00000715608, ENST00000798770, ENST00000798771, ENST00000798772, ENST00000798773, ENST00000798774, ENST00000798775, ENST00000798776, ENST00000798777, ENST00000798778, ENST00000798779, ENST00000798780

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419511 — 5 exons

Exon	Start	End
ENSE00001599091	218930358	218930636
ENSE00001602536	218921690	218921760
ENSE00001640444	218906839	218907046
ENSE00001781613	218927163	218927254
ENSE00004027375	218900811	218901171

Expression profiles

Bgee: expression breadth broad, 98 present calls, max score 79.80.

Top tissues by expression

98 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.80	gold quality
pituitary gland	UBERON:0000007	71.41	gold quality
adenohypophysis	UBERON:0002196	70.46	gold quality
cortical plate	UBERON:0005343	69.44	gold quality
prefrontal cortex	UBERON:0000451	66.41	gold quality
superior frontal gyrus	UBERON:0002661	66.00	gold quality
frontal cortex	UBERON:0001870	65.24	gold quality
right frontal lobe	UBERON:0002810	63.98	gold quality
cerebellar hemisphere	UBERON:0002245	63.55	gold quality
cerebellar cortex	UBERON:0002129	63.49	gold quality
right hemisphere of cerebellum	UBERON:0014890	63.48	gold quality
cerebellum	UBERON:0002037	63.39	gold quality
Brodmann (1909) area 9	UBERON:0013540	63.01	gold quality
islet of Langerhans	UBERON:0000006	62.83	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	62.67	gold quality
cerebral cortex	UBERON:0000956	62.55	gold quality
primary visual cortex	UBERON:0002436	62.42	gold quality
brain	UBERON:0000955	62.30	gold quality
anterior cingulate cortex	UBERON:0009835	62.20	gold quality
hypothalamus	UBERON:0001898	62.13	gold quality
nucleus accumbens	UBERON:0001882	60.75	gold quality
putamen	UBERON:0001874	59.99	gold quality
caudate nucleus	UBERON:0001873	59.48	gold quality
lymph node	UBERON:0000029	59.36	gold quality
placenta	UBERON:0001987	58.83	gold quality
substantia nigra	UBERON:0002038	56.86	gold quality
temporal lobe	UBERON:0001871	56.14	gold quality
amygdala	UBERON:0001876	56.07	gold quality
Ammon’s horn	UBERON:0001954	55.43	gold quality
gall bladder	UBERON:0002110	54.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.