CDRT3

Summary

CDRT3 (CMT1A duplicated region transcript 3, HGNC:14382) is a long non-coding RNA gene on chromosome 17p12.

At a glance

• Clinical variants (ClinVar): 1 total

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:14382
Approved symbol	CDRT3
Name	CMT1A duplicated region transcript 3
Location	17p12
Locus type	RNA, long non-coding
Status	Approved
Entrez	94145
RNAcentral	URS0000BC4580 — lncRNA, 538 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

1 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	1
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1003546377 (17:15471127 T>G), RS1004020967 (17:15471346 C>T), RS1006372704 (17:15470041 G>A,C), RS1008163796 (17:15471850 C>T), RS1009650224 (17:15471821 G>A), RS1009661343 (17:15471693 A>G), RS1010659186 (17:15470664 T>C), RS1012843989 (17:15471290 A>C,G), RS1012916223 (17:15470095 A>C), RS1013511936 (17:15472285 C>G), RS1013646974 (17:15472770 C>A), RS1015211906 (17:15471921 T>G), RS1015828975 (17:15472333 A>G), RS1018658305 (17:15471251 T>C), RS1019711760 (17:15470236 A>G)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.