CEBPB-AS1

Summary

CEBPB-AS1 (CEBPB antisense RNA 1, HGNC:51226) is a long non-coding RNA gene on chromosome 20q13.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51226
Approved symbol	CEBPB-AS1
Name	CEBPB antisense RNA 1
Location	20q13.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000277449
Ensembl biotype	lncRNA
Entrez	101927559
RNAcentral	URS00007E368D — lncRNA, 2973 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000613921, ENST00000751366, ENST00000751367

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000613921 — 6 exons

Exon	Start	End
ENSE00003712189	50189998	50190285
ENSE00003715924	50189456	50189561
ENSE00003716771	50184598	50186420
ENSE00003734448	50191268	50191498
ENSE00003747751	50188543	50188627
ENSE00003749839	50187013	50187127

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 88.77.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.77	gold quality
calcaneal tendon	UBERON:0003701	74.76	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.35	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.32	gold quality
skeletal muscle tissue	UBERON:0001134	73.05	gold quality
muscle of leg	UBERON:0001383	72.74	gold quality
gastrocnemius	UBERON:0001388	72.14	gold quality
left ovary	UBERON:0002119	71.68	gold quality
ovary	UBERON:0000992	71.09	gold quality
popliteal artery	UBERON:0002250	70.47	gold quality
tibial artery	UBERON:0007610	70.46	gold quality
right ovary	UBERON:0002118	69.75	gold quality
descending thoracic aorta	UBERON:0002345	69.50	gold quality
thoracic aorta	UBERON:0001515	67.94	gold quality
ascending aorta	UBERON:0001496	67.82	gold quality
right coronary artery	UBERON:0001625	67.30	gold quality
tibial nerve	UBERON:0001323	67.20	gold quality
body of uterus	UBERON:0009853	66.25	gold quality
primary visual cortex	UBERON:0002436	65.98	gold quality
left uterine tube	UBERON:0001303	65.42	gold quality
left coronary artery	UBERON:0001626	65.10	gold quality
myometrium	UBERON:0001296	64.86	gold quality
bone marrow	UBERON:0002371	64.76	gold quality
putamen	UBERON:0001874	64.75	gold quality
bone marrow cell	CL:0002092	64.74	silver quality
muscle layer of sigmoid colon	UBERON:0035805	64.69	gold quality
right atrium auricular region	UBERON:0006631	64.49	gold quality
caudate nucleus	UBERON:0001873	64.27	gold quality
superior frontal gyrus	UBERON:0002661	64.06	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	63.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.71

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Silencing of CEBPB-AS1 modulates CEBPB expression and resensitizes BRAF-inhibitor resistant melanoma cells to vemurafenib. (PMID:32467529)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.