CECR7

Summary

CECR7 (cat eye syndrome chromosome region, candidate 7, HGNC:1845) is a unprocessed pseudogene on chromosome 22q11.1.

At a glance

• Gene type: non-coding (transcribed_unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:1845
Approved symbol	CECR7
Name	cat eye syndrome chromosome region, candidate 7
Location	22q11.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	SAHL1
Ensembl gene	ENSG00000237438
Ensembl biotype	transcribed_unprocessed_pseudogene
Entrez	100130418
RNAcentral	URS0000CCE07B — lncRNA, 4053 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unprocessed_pseudogene

ENST00000636648

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000636648 — 3 exons

Exon	Start	End
ENSE00001699373	17044873	17045000
ENSE00001726793	17047324	17047426
ENSE00003794480	17046346	17046444

Expression profiles

Bgee: expression breadth ubiquitous, 281 present calls, max score 94.36.

Top tissues by expression

290 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
endothelial cell	CL:0000115	94.36	gold quality
epithelium of bronchus	UBERON:0002031	92.30	gold quality
bronchus	UBERON:0002185	92.19	gold quality
bronchial epithelial cell	CL:0002328	92.16	gold quality
subthalamic nucleus	UBERON:0001906	92.11	gold quality
ventral tegmental area	UBERON:0002691	91.92	gold quality
mucosa of urinary bladder	UBERON:0001259	91.80	gold quality
lateral globus pallidus	UBERON:0002476	91.70	gold quality
superior vestibular nucleus	UBERON:0007227	91.34	gold quality
substantia nigra pars reticulata	UBERON:0001966	91.06	gold quality
inferior vagus X ganglion	UBERON:0005363	90.96	gold quality
pons	UBERON:0000988	90.93	gold quality
substantia nigra pars compacta	UBERON:0001965	90.83	gold quality
buccal mucosa cell	CL:0002336	90.78	gold quality
cardia of stomach	UBERON:0001162	90.64	gold quality
renal medulla	UBERON:0000362	90.49	gold quality
cervix squamous epithelium	UBERON:0006922	90.37	silver quality
trigeminal ganglion	UBERON:0001675	90.31	gold quality
medulla oblongata	UBERON:0001896	90.30	gold quality
dorsal plus ventral thalamus	UBERON:0001897	90.30	gold quality
lateral nuclear group of thalamus	UBERON:0002736	90.11	gold quality
choroid plexus epithelium	UBERON:0003911	89.92	gold quality
nasal cavity epithelium	UBERON:0005384	89.91	silver quality
dorsal root ganglion	UBERON:0000044	89.65	gold quality
mucosa of paranasal sinus	UBERON:0005030	89.56	silver quality
CA1 field of hippocampus	UBERON:0003881	89.17	gold quality
saphenous vein	UBERON:0007318	89.12	gold quality
cranial nerve II	UBERON:0000941	89.06	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.22	gold quality
olfactory bulb	UBERON:0002264	88.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.18

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• This chimeric transcription unit is formed from three duplicons in the pericentromeric region of chromosome 22q. (PMID:12483300)
• cycl gene from human 22nd chromosome that encodes the lung adenocarcinoma antigne recognized by the lung cancer specific monoclonal antibodies (PMID:8564085)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.